Results 41 to 50 of about 8,933 (160)

Do We Really Know How to Manage Anticoagulated Patients for Periodontal Nonsurgical Therapy? An Observational Cohort Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives The aim of this work is to assess and compare the impact of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKA) during and immediately after periodontal nonsurgical therapy. Materials and Methods A prospective observational cohort study was conducted with patients who presented a history of cardiovascular disease ...
F. Berton, A. Rapani, F. Costantinides, V. Nicolin, D. Cuhureanu, R. Di Lenarda   +5 more
wiley   +1 more source

Inside the ‘Black Box’ of Pharmaceuticalisation: NICE, the Permissive Principle and the Case of Anticoagulants

Sociology of Health &Illness, Volume 48, Issue 8, November 2026.
ABSTRACT Sociological interest in pharmaceuticalisation continues to grow, especially regarding the expansion of pharmaceutical use in society. This article presents the first major empirical study focusing on the directionality of pharmaceuticalisation by taking cost‐effectiveness assessment and regulation of anticoagulants in England by the National ...
John Abraham, Gowree Balendran
wiley   +1 more source

Dabigatran etexilate dosing and monitoring in Aotearoa New Zealand [PDF]

, 2020
Introduction Dabigatran etexilate is a direct thrombin inhibitor that has become widely used in New Zealand. It has been available and fully subsidised in New Zealand since July 2011.
Simpson, Bryan Henry
core   +1 more source

Recurrent Large‐Vessel Occlusive Stroke Requiring Repeated Mechanical Thrombectomy in Severe Dilated Cardiomyopathy With Extremely Low Left Ventricular Ejection Fraction and HIV Screening Positivity: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Severe dilated cardiomyopathy with markedly reduced left ventricular ejection fraction can rarely present as recurrent large‐vessel occlusive stroke. This case demonstrates that timely mechanical thrombectomy and sustained anticoagulation are crucial for neurological recovery and secondary prevention, while HIV screening positivity adds ...
Jing Xu, Liangxu Xiang, Yanghua Tian
wiley   +1 more source

Fruquintinib: Mechanism of Action, Clinical, and Translational Science

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Fruquintinib is a highly selective, oral inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3) that was approved, including in China, the United States, and the European Union, for the treatment of previously treated metastatic colorectal cancer (mCRC).
Xiaofei Zhou, Arvind Dasari, Jin Li, Caly Chien, Qi Dong, Lucy Chen, Lixian Dong, Neeraj Gupta   +7 more
wiley   +1 more source

Practical use of dabigatran etexilate for stroke prevention in atrial fibrillation [PDF]

, 2013
Atrial fibrillation (AF) is associated with an increased risk of thromboembolism, and is the most prevalent factor for cardioembolic stroke. Vitamin K antagonists (VKAs) have been the standard of care for stroke prevention in patients with AF since the ...
Merkely, Béla Péter, Connolly SJ, Widimský, P, Christory F, Kiss, R G, Dan, G-A, Hatala, R, Vinereanu, D, Kher, A, Pieske, B, Kher A, Meier, B, Potpara, T, Huber K, Stępińska, J, Connolly, S J, Christory, F, Merkely, B, Huber, K, Klun, N Vene, Dan GA, Kiss, Róbert Gábor, Connolly, S. J., Pieske, B., Huber, K., Vinereanu, D., Christory, F., Hatala, R., Klun, N. Vene, Kher, A., Dan, G.‐A., Potpara, T., Stępińska, J., Meier, B., Widimský, P., Kiss, R. G., Merkely, B.   +36 more
core   +2 more sources

Type of anaesthesia and the safety and efficacy of thromboprophylaxis with enoxaparin or dabigatran etexilate in major orthopaedic surgery: pooled analysis of three randomized controlled trials

Thrombosis Journal, 2012
Background There has been a shift towards greater use of neuraxial over general anaesthesia for patients undergoing total hip or knee arthroplasty. Furthermore, suggestions that peripheral nerve block may reduce adverse effects have recently been put ...
Rosencher Nadia, Noack Herbert, Feuring Martin, Clemens Andreas, Friedman Richard J, Eriksson Bengt I   +5 more
doaj   +1 more source

Using Pharmacovigilance Data for Signal Detection of Drug Interactions for Rosuvastatin

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT The 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase inhibitor rosuvastatin is a substrate of breast cancer resistance protein (BCRP). BCRP inhibition increases rosuvastatin plasma concentrations and may result in concentration‐dependent muscle toxicity, at worst rhabdomyolysis.
Ronja Levomäki, Päivi Hirvensalo, Aleksi Tornio, Anne M. Filppula   +3 more
wiley   +1 more source

Systemic Thrombolysis in Acute Ischemic Stroke after Dabigatran Etexilate Reversal with Idarucizumab—A Case Report

, 2017
Introduction Idarucizumab is a reversal agent for dabigatran etexilate. By reversing the anticoagulating effect of dabigatran etexilate with idarucizumab (Praxbind), patients presenting with an acute ischemic stroke can now be eligible for thrombolysis ...
Tireli, Derya, Nordling, Mette Maria, Mette Maria Nordling, Jun He, Troels Wienecke, Wienecke, Troels, He, Jun, Derya Tireli   +7 more
core   +1 more source

Safety and Effectiveness of Glecaprevir/Pibrentasvir in Children and Adolescents With Chronic Hepatitis C: Reports From All‐Case Post‐Marketing Surveillance in Japan

Hepatology Research, Volume 56, Issue 8, Page 1202-1212, August 2026.
ABSTRACT Aim The aim of this all‐case post‐marketing study was to evaluate the real‐world safety and effectiveness in all children and adolescents with chronic hepatitis C with or without compensated cirrhosis treated with glecaprevir/pibrentasvir (G/P) in Japan. Methods This prospective, observational post‐marketing surveillance study was conducted at
Tatsuki Mizuochi, Katsuyoshi Kawana, Mariko Kobayashi, Eri Iwashita, Itaru Iwama, Daiki Abukawa, Hitoshi Tajiri   +6 more
wiley   +1 more source