Results 121 to 130 of about 57,080 (289)

First Commercial Company Leverages DAF-MIT Maneuver ID Challenge to Advance AI

open access: yes, 2023
The Department of the Air Force-MIT Artificial Intelligence Accelerator (AIA) announced that Crowdbotics is the first company to successfully leverage the Maneuver Identification Challenge to advance the field of AI. The DAF-MIT AIA Maneuver ID Challenge

core  

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin   +11 more
wiley   +1 more source

Fast eikonal phase retrieval for high‐throughput beamlines

open access: yesJournal of Synchrotron Radiation, EarlyView.
Fast eikonal phase retrieval with complementary local (sub‐pixel) and non‐local (multi‐pixel) solvers strongly suppresses nonlinear streak artefacts in long‐distance propagation‐based phase‐contrast micro‐tomography at high computational efficiency.A fast eikonal phase retrieval formulation is introduced that accelerates eikonal phase retrieval by more
Alessandro Mirone   +5 more
wiley   +1 more source

Evolution of hierarchical phase‐contrast tomography on the European Synchrotron beamlines BM05 and BM18: a whole adult human brain imaging case study

open access: yesJournal of Synchrotron Radiation, EarlyView.
The evolution of hierarchical phase‐contrast tomography (HiP‐CT) from its origins at the BM05 beamline to its transition to BM18 (ESRF‐EBS) is shown. The novel hardware and scanning approach developments resulted in significantly improved data quality, resolution, sensitivity and speed.
Hector Dejea   +9 more
wiley   +1 more source

Proteostasis of organelles in aging and disease

open access: yesThe FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi   +5 more
wiley   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

open access: yesThe FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo   +4 more
wiley   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

open access: yesThe FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia   +7 more
wiley   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Web 2.0-Werkzeuge und Apps im regulären DaF-Unterricht

open access: yesMedienimpulse, 2018
Johanna Chardaloupa, Aimi Jõesalu
doaj   +1 more source

Identification of somatic phenotypes caused by daf-21/Hsp90 mutation in Caenorhabditis elegans

open access: yes, 2005
P(論文)Hsp90はHeat shock proteinファミリーの一員であり、その分子シャペロンとしての機能は種を越えて良く保存されている。これまでの研究により、多くのタンパク質がその立体構造保持のために、Hsp90の機能を必要とすることが明らかとなっているが、多細胞生物におけるHsp90の機能喪失が細胞や組織の機能に与える影響という観点からの解析はあまり例を見ない。この度、われわれは線虫C.
山口, 泰典   +5 more
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