Results 131 to 140 of about 391,464 (281)

Heating and cooling a tri-level house with a hydronic baseboard-valance system [PDF]

open access: yes, 1966
Cover title.Prepared as part of an investigation conducted by the Engineering Experiment Station, University of Illinois at Urbana ...
Fitch, Calvin H.   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

ANALYSIS OF ELECTRICITY CONSUMPTION USING THE COMPONENT METHOD OF PERIODICALLY CORRELATED RANDOM PROCESSES

open access: yesКомпютерні системи та інформаційні технології
Contemporary energy systems, considering the diverse challenges emerging within energy infrastructure, require advanced analytical methodologies for electricity consumption forecasting.
Андрій ВОЛОЩУК   +3 more
doaj   +1 more source

Development of a renewable hybrid power plant with extended utilization of pumped storage unit equipment [PDF]

open access: yes, 2019
The scheme of a renewable hybrid power plant with the extended use of the installed equipment of the pumped storage unit for the conversion of the photovoltaic and wind generators direct current to the alternating one is proposed.
Chervonenko, I.   +2 more
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Evaluation of Sampling Strategies on Load Estimation For Illinois River at Highway 59 [PDF]

open access: yes, 2003
This study investigated the precision and accuracy of the two load calculation techniques. The study compared total phosphorus loads calculated by integration of Arkansas Water Resources Center (AWRC) intensive sampling data to loads calculated by a ...
Nelson, M. A., Soerens, T. S.
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Balancing stress and recovery in sports [PDF]

open access: yes, 2010
To reach elite level in sports, athletes have to start their intensive and time-consuming training at an early stage. The road to the top is a stressful one, not only due to the physiological stress of training, but also caused by psychological and ...
Brink, Michel Sanne,
core   +2 more sources

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