Results 121 to 130 of about 62,885 (274)

Cyber Insurance Design for Load Variation and Load Curtailment in Distribution Grids [PDF]

A growing number of renewable energy resources (RES) is continuously integrated into power systems contributing towards the green energy and net zero transition.
Pan, Shijie, Lakshminarayana, Subhash, Konstantinou, Charalambos   +2 more
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Daily and Accumulated Training-to-Match Load Ratios in Professional Soccer: The Influence of Starting Status and Playing Position Across a Full Competitive Season

Data
Introduction: Monitoring training load is essential in elite soccer to optimize performance and reduce injury risk. The training-to-match load ratio (TMr) has emerged as a useful metric to contextualize training demands relative to competitive match ...
Alejandro Sierra-Casas, Daniel Castillo, Filipe Manuel Clemente, Alejandro Rodríguez-Fernández   +3 more
doaj   +1 more source

ESTIMATING CALORIC EXPENDITURE USING THE PHYSICAL ACTIVITY INDEX (PAI) IN CHILDREN AND ADOLESCENTS PERFORMING A MULTISTAGE MAXIMAL EXERCISE TEST [PDF]

, 2014
PURPOSE: The primary purposes of this investigation were (a) to examine the validity of the PAI, (b) to develop a statistical model to predict cumulative Kcal expenditure using PAI as the predictor variable and (c) to develop a statistical model to ...
Gairola, Anjuli
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Diminished circadian and ultradian rhythms of human brain activity in pathological tissue in vivo

Nature Communications
Chronobiological rhythms, such as the circadian rhythm, have long been linked to neurological disorders, but it is currently unknown how pathological processes affect the expression of biological rhythms in the brain.
Christopher Thornton, Mariella Panagiotopoulou, Fahmida A. Chowdhury, Beate Diehl, John S. Duncan, Sarah J. Gascoigne, Guillermo Besne, Andrew W. McEvoy, Anna Miserocchi, Billy C. Smith, Jane de Tisi, Peter N. Taylor, Yujiang Wang   +12 more
doaj   +1 more source

The circadian clock gene period regulates the composition and daily bacterial load of the gut microbiome in Drosophila melanogaster [PDF]

While Drosophila melanogaster serves as a crucial model for investigating both the circadian clock and gut microbiome, our understanding of their relationship in this organism is still limited. Recent analyses suggested that the Drosophila gut microbiome
Romoli O., Sandrelli F., Battistolli M., Varponi I.   +3 more
core   +1 more source