Results 111 to 120 of about 963,699 (298)

Investigating age and regional effects on the relation between the incidence of heat-related ambulance transport and daily maximum temperature or WBGT. [PDF]

Environ Health Prev Med, 2021
Ueno S, Hayano D, Noguchi E, Aruga T.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Night-Time Temperature Reprieves Enhance the Thermal Tolerance of a Symbiotic Cnidarian

Frontiers in Marine Science, 2019
Responses of cnidarian-Symbiodiniaceae associations to warming are determined, in part, by high-frequency temperature variability. Yet, the role of such variability in determining specific maximum temperature thresholds of cnidarian holobionts (the ...
Shannon G. Klein, Kylie A. Pitt, Cathy H. Lucas, Shiou-Han Hung, Sebastian Schmidt-Roach, Manuel Aranda, Carlos M. Duarte   +6 more
doaj   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Investigating the Impact of Climate Change on Extreme Temperature and Precipitation in the Sefidrood Basin Based on CMIP6 Models [PDF]

علوم آب و خاک
In the present study, the impact of climate change on maximum temperature and daily precipitation in 16 weather stations was investigated in the Sefidrood Basin from 2023 to 2052.
M.J. Zareian, R. Seraj Ebrahimi, H. Dehban   +2 more
doaj  

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Radial growth and its temporal stability of Dahurian larch in the southern boreal forest: Divergent trends during climate warming and warming hiatus

Forest Ecosystems
Climate warming has reshaped the structure and function of global boreal forest with expected negative impacts at its southern margins. A warming hiatus has occurred in many high-latitude regions in recent decades, but its impacts on tree growth in the ...
Zhongtong Peng, Enzai Du, Yang Tang, Tao He, Yuehan Tian   +4 more
doaj   +1 more source

Trends in temperature and growing season length in idaho-usa during the past few decades

Revista Brasileira de Meteorologia, 2015
This study attempts to provide new information on seasonal and annual trends, on a regional scale, using records of daily air temperature over Idaho, USA, through the analysis of the Growing Season Length (GSL), and maximum and minimum air temperature ...
Carlos Antonio Costa dos Santos, Tantravahi Venkata Ramana Rao, Ricardo Alves de Olinda   +2 more
doaj   +1 more source