Results 71 to 80 of about 1,771,596 (264)

La configuración de la identidad privada: diarios y libros de memorias en la Baja Edad Media

Historia. Instituciones. Documentos, 2002
El objetivo del presente artículo es analizar la presencia de anotaciones de carácter privado en libros de cuentas pertenecientes a mercaderes y artesanos valencianos de los años ginales de la Edad Media, y de qué modo esa presencia revela la ...
María Luz Mandingorra Llavata
doaj  

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Construction and Application of Dynamic Threshold Model for Agricultural Drought Grades Based on Near-Infrared and Short-Wave Infrared Bands for Spring Maize

Remote Sensing
Maize (Zea mays L.) is one of the most important grain crops in the world. Drought caused by climate change in recent years may greatly threaten water supply and crop production, even if the drought only lasts for a few days or weeks.
Xia Wu, Peijuan Wang, Yanduo Gong, Yuanda Zhang, Qi Wang, Yang Li, Jianping Guo, Shuxin Han   +7 more
doaj   +1 more source

A validation study of the Eurostat harmonised European time use study (HETUS) diary using wearable technology

BMC Public Health, 2019
Background The central aim was to examine the accuracy of the full range of daily activities recorded in self-report time-use diaries against data from two objective passive data collection devices (wearable camera and accelerometer) serving as criterion
Teresa Harms, Jonathan Gershuny, Aiden Doherty, Emma Thomas, Karen Milton, Charlie Foster   +5 more
doaj   +1 more source

Record occurrence and record values in daily and monthly temperatures

, 2013
We analyze the occurrence and the values of record-breaking temperatures in daily and monthly temperature observations. Our aim is to better understand and quantify the statistics of temperature records in the context of global warming.
Hense, Andreas, Krug, Joachim, Wergen, Gregor   +2 more
core   +1 more source

Modeling Infection with Multi-agent Dynamics [PDF]

, 2012
Developing the ability to comprehensively study infections in small populations enables us to improve epidemic models and better advise individuals about potential risks to their health.
J. Stehle, L. Hufnagel, L. Isella, M. Salathe, S. Eubank   +4 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source