Results 231 to 240 of about 5,119,262 (363)

Experimental study on fracture and fragmentation characteristics of laminated rocks under impact loading. [PDF]

Sci Rep
Deng D, Li Y, Guo L, Liu G, Hua J.
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Identification of frame geometry and boundary conditions from free-vibration modal signatures. [PDF]

Sci Rep
Karimi-Asrami A, Jafari-Talookolaei RA, Mardani A, Jumaev E, Mikhliev O.   +4 more
europepmc   +1 more source

Some remarks on liability for the damage caused by the seeping of water from the premises located at the upper floor to those located at the lower floor

, 2010
Palmirski, Tomasz
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Cross-Sectional Multicenter Biomonitoring Study on Genotoxicity and Oxidative DNA Damage in Oncology Healthcare Workers from Seven Italian Hospitals. [PDF]

J Xenobiot
Ursini CL, Di Gennaro G, Buresti G, Maiello R, Fresegna AM, Ciervo A, Gentile M, Di Basilio V, Beltramini S, Gaggero D, Rigamonti N, Maccari E, Zorzetto G, Maiolino P, Di Filippo P, Bilancio MC, Baldo P, Martinello V, Di Mattia A, Esposito C, Nardulli P, Laforgia M, Visconti MV, Vitali M, Omodeo-Salè E, Cavallo D.   +25 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dynamic damage and crack propagation of granite under thermal shock: DEM modeling insights. [PDF]

Sci Rep
Su L, Li H, Chi Q, Yang X, Gao X, Huang X.   +5 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Downhill Running-Induced Muscle Damage in Trail Runners: An Exploratory Study Regarding Training Background and Running Gait. [PDF]

Sports (Basel)
Martinez-Navarro I, Vicente-Mampel J, López-Grueso R, Suarez-Alcazar MP, Vilar-Fabra C, Collado-Boira E, Hernando C.   +6 more
europepmc   +1 more source