Results 271 to 280 of about 5,119,262 (363)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Gaia serial charge transfer inefficiency modelling and radiation damage study

C. Pagani, N. C. Hambly, M. Davidson, N. Rowell, C. Crowley, R. Collins, F. van Leeuwen, G. M. Seabroke, A. Holland, M. A. Barstow, D. Gareth Evans   +10 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Special Issue "Advances in the Prevention and Treatment of Ischemic Diseases". [PDF]

Int J Mol Sci
Plotnikov EY.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

YOLO-ERCD: An Upgraded YOLO Framework for Efficient Road Crack Detection. [PDF]

Sensors (Basel)
Li X, Chu Y, Chan T, Lo WL, Fu H.
europepmc   +1 more source

Supervised Machine Learning Algorithms in Predicting Damaged Cargo: A Portuguese Logistics & Transportation Company Case Study

Vale, Alice Lourenço
openalex   +1 more source

Effect of green tea supplementation on muscle damage and muscle soreness

, 2017
Willian Gabriel Felicio da [UNESP] Silva
openalex   +1 more source

Garlic-YOLO-DD: a lightweight object detection algorithm for garlic damage detection. [PDF]

Front Plant Sci
Gao Y, Ma X, Xia Z, Qi T, Wang X, He Z, Chen G.   +6 more
europepmc   +1 more source

Assessment of wind-induced fatigue life for transmission tower-line systems incorporating joint probability distribution of wind speed and direction. [PDF]

Sci Rep
Wu S, Liu H, Zhang J, You Y.
europepmc   +1 more source