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A VIBRATIONAL DAMAGE MODEL FOR PEARS BASED ON FATIGUE ACCUMULATIVE DAMAGE THEORY [PDF]

Engenharia Agrícola
Fatigue vibration is a primary cause of fruit damage during transportation. Drawing on the Palmgren–Miner fatigue accumulation damage theory and the correlation between fruit vibration damage characteristics and external vibration excitation, this paper ...
Chenxu Zhao, Yuchi Li, Xue Huang, Shujie Song   +3 more
doaj   +1 more source

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Abdi R, Anders HJ, Anders HJ, Anders HJ, Bruhl H, Burne-Taney MJ, Feng L, Fituri O, Fujinaka H, Garcia GE, Grone HJ, Keane MP, Mack M, Miura M, Murphy PM, Nath KA, Perez de Lema G, Rollins BJ, Romagnani P, Segerer S, Segerer S, Segerer S, Tang WW, Taub DD, Tesch GH, Tokuda A, Topham PS, Vielhauer V, Vielhauer V, Wada T, Wang Y, Wenzel U, Wu X, Wu X, Zernecke A   +34 more
core   +1 more source

Study on a Damage Constitutive Model for Surrounding Rock Under the Coupling Effects of Initial Damage and Cyclic Blasting

Applied Sciences
To reveal the cumulative damage mechanism of surrounding rock with initial damage under cyclic blasting loads during tunnel reconstruction and expansion, this study combines theoretical modeling, split Hopkinson pressure bar (SHPB) tests, and three ...
Kaiyi Xie, Bo Wu
doaj   +1 more source

PE-HD fatigue damage accumulation under variable loading based on various damage models

eXPRESS Polymer Letters, 2017
Despite numerous studies on fatigue of polymer materials under variable loading, there is little work on highdensity polyethylene (PE-HD). In this context, an experimental analysis for determining the fatigue strength of PE-100, under constant and ...
M. Bourchak, A. Aid
doaj   +1 more source

Vibration Fatigue Damage Accumulation of Ti–6Al–4V under Constant and Sequenced Variable Loading Conditions

Metals, 2018
This study aims to investigate the effect of loading factors on damage accumulation under variable amplitude vibration (VAV). Vibration fatigue experiments are conducted under both constant amplitude vibration (CAV) and VAV loading cases.
Jiewei Lin, Weidong Li, Shuo Yang, Junhong Zhang   +3 more
doaj   +1 more source

Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons [PDF]

, 2014
Alternative splicing—the production of multiple messenger RNA isoforms from a single gene—is regulated in part by RNA binding proteins. While the RBPs transformer2 alpha (Tra2α) and Tra2β have both been implicated in the regulation of alternative ...
Austin, Caroline A., Best, Andrew, Chabot, Benoit, Cheong Lee, Ka, Cowell, Ian G., Curk, Tomaz, Dalgliesh, Caroline, Danilenko, Marina, Elliott, David J., Hong, Elaine, Hussain, Rafiq, James, Katherine, Keavney, Bernard, Kheirolahi-Kouhestani, Mahsa, Klinck, Roscoe, Santibanez Koref, Mauro, Tyson-Capper, Alison, Venables, Julian P., Wipat, Anil, Xu, Yaobo   +19 more
core   +2 more sources

Real-Time Loss Tools: Open-Source Software for Time- and State-Dependent Seismic Damage and Loss Calculations – Features and Application to the 2023 Türkiye-Syria Sequence

Seismica
During a seismic sequence, the action of each earthquake has the potential to damage and weaken exposed structures, causing their fragility to change, and increasing their likelihood of being further damaged by subsequent earthquakes.
Cecilia Nievas, Helen Crowley, Graeme Weatherill, Fabrice Cotton   +3 more
doaj   +1 more source

Induction of Stress Granule Assembly is Essential for the Orchestration of DNA Damage Response [PDF]

, 2008
DNA damage provokes several responses including DNA repair, cell cycle regulation and apoptosis that collectively represent the DNA damage response (DDR).
Nicole S. Verkaik, Stephan Persengiev
core   +1 more source

The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function [PDF]

, 2015
Poly (ADP-ribose) is synthesized at DNA single-strand breaks and can promote the recruitment of the scaffold protein, XRCC1. However, the mechanism and importance of this process has been challenged.
Breslin, Claire, Caldecott, Keith W, Hanzlikova, Hana, Hornyak, Peter, Oliver, Antony W, Ridley, Andrew, Rulten, Stuart L   +6 more
core   +3 more sources

Ensuring Seismic Resistance of Reinforced Concrete Buildings

Железобетонные конструкции
There are a large number of works on a comprehensive assessment of the seismic resistance of buildings and structures. However, these studies, as a rule, do not take into account the random nature of the seismic impact, which is a pronounced non ...
O. V. Mkrtychev, A. A. Reshchetov
doaj   +1 more source