Results 31 to 40 of about 1,392,331 (344)

Aging as a consequence of misrepair -- A novel theory of aging [PDF]

open access: yes, 2009
It is now increasingly realized that the underlying mechanisms which govern aging is a complex interplay of genetic regulation and damage accumulation. Aging as a result of accumulation of ‘faults’ on cellular and molecular levels, has been
Arne Wunderlin   +3 more
core   +4 more sources

Lifetime of High-Parameter Structures under Repeated and Prolonged Thermomechanical Influences

open access: yesМеханика машин, механизмов и материалов, 2021
The article considers the main provisions and equations of the applied theory of inelasticity, which belongs to the class of flow theories under combined hardening.
Valentin S. Bondar, Dmitriy R. Abashev
doaj   +1 more source

Bone creep-fatigue damage accumulation

open access: yesJournal of Biomechanics, 1989
Creep and fatigue tests were performed on human femoral cortical bone and the results were compared to a cumulative damage model for bone fracture. Fatigue tests in tension, compression, and reversed loading with a tensile mean stress were conducted at 2 Hz and 0.02 Hz.
W E, Caler, D R, Carter
openaire   +2 more sources

The DNA damage response acts as a safeguardagainst harmful DNA–RNA hybrids ofdifferent origins [PDF]

open access: yes, 2019
Despite playing physiological roles in specific situations, DNA–RNA hybrids threat genome integrity. To investigate how cells do counteract spontaneous DNA–RNA hybrids, here we screen an siRNA library covering 240 human DNA damage response (DDR) genes ...
Aguilera López, Andrés   +5 more
core   +1 more source

A Reliability-Based Framework for Damage Accumulation Due to Multiple Earthquakes: A Case Study on Bridges

open access: yesInfrastructures, 2023
Damage accumulation due to multiple seismic impacts over time has a significant effect on the residual service life of the bridge. A reliability-based framework was developed to make decisions in bridge maintenance activities.
Nilupa Herath   +5 more
doaj   +1 more source

Mechanisms of sensorineural cell damage, death and survival in the cochlea. [PDF]

open access: yes, 2015
The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well ...
Ryan, Allen F, Wong, Ann CY
core   +1 more source

Life-cycle assessment method for key parts of an electric locomotive body

open access: yes机车电传动, 2022
In respect of the fatigue crack failure of the electric locomotive body under the cyclic excitation, the dynamic strain test was carried out on the key parts, and the fatigue life of the locomotive body was researched based on standard loads.
ZENG Yanjun   +4 more
doaj  

The Effects of Ultraviolet Light on Anthocyanin Accumulation in the Adventitious Roots of Sedum wrightii (Crassulaceae) [PDF]

open access: yes, 2018
Several studies have supported the idea that anthocyanin accumulation may be a possible protection mechanism in plants against DNA damage caused by ultraviolet radiation (UV).
Gravatt, Dennis A.   +2 more
core   +2 more sources

In-cascade ionization effects on defect production in 3C silicon carbide

open access: yesMaterials Research Letters, 2017
Understanding how energy deposited in electronic and atomic subsystems may affect defect dynamics is a long-standing fundamental challenge in materials research.
Haizhou Xue   +2 more
doaj   +1 more source

Damage Distribution Map Based Damage Accumulation Calculation Approach for Welded Joints

open access: yesMetals, 2023
Fatigue damage accumulation under variable amplitude loadings is vital for the life prediction of welded structures. An approach based on damage distribution mapping is presented. S-N curves of welded joints are utilized to construct fatigue damage zones,
Haochun Duan, Zhang Dang, Guoqian Wei
doaj   +1 more source

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