Results 51 to 60 of about 1,392,331 (344)

A statistically self-consistent fatigue damage accumulation model including load sequence effects under spectrum loading [PDF]

Fracture and Structural Integrity, 2016
A probabilistic methodology is proposed to evaluate fatigue damage accumulation and fatigue lives of specimens under variable amplitude loading. With probabilistic modifications in the present model, the calculative consistency is achieved between ...
Chen Xianmin, Sun Qin, Dui Hongna, Fan Junling   +3 more
doaj   +2 more sources

Fatigue Analysis and Load Spectrum Generation for Wing‐Fuselage Lug Joint With a Focus on Human Safety Transport Category Aircraft

Engineering Reports
This research work focuses on fluctuating load spectrum generation and fatigue analysis of a wing‐fuselage attachment lug joint, in accordance with the requirements outlined in 14 CFR Part 25 for transport category aircraft.
Rajadurai Murugesan, Srikanth Holalu Venkataraman, Pradeep Kumar Sahoo, Praveena Bindiganavile Anand, Rithick Rithick, Muhammad Imam Ammarullah   +5 more
doaj   +1 more source

Removal of luminal content protects the small intestine during hemorrhagic shock but is not sufficient to prevent lung injury. [PDF]

, 2013
The small intestine plays a key role in the pathogenesis of multiple organ failure following circulatory shock. Current results show that reduced perfusion of the small intestine compromises the mucosal epithelial barrier, and the intestinal contents ...
Altshuler, Angelina E, Heller, Michael J, Modestino, Augusta E, Penn, Alexander H, Richter, Michael D, Schmid-Schönbein, Geert W   +5 more
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Study on the Potential of New Load-Carrying Capacity Descriptions for the Service Life Calculations of Gears

Machines
Calculating the service life of gears under variable loads requires a description of the load-carrying capacity. The current standard for this is the use of the S/N curve.
Daniel Vietze, Josef Pellkofer, Karsten Stahl   +2 more
doaj   +1 more source

High-cycle fatigue damage accumulation in paper

Communications Materials, 2020
Paper is a ubiquitous material used in a range of applications, many of which expose it to fatigue loading. Here, a detailed study of the mechanical response of paper during high‐cycle fatigue loading is reported, with fiber fracture found to be a key ...
Yoon Joo Na, Sarah A. Paluskiewicz, Christopher L. Muhlstein   +2 more
doaj   +1 more source

Siglec receptors impact mammalian lifespan by modulating oxidative stress. [PDF]

, 2015
Aging is a multifactorial process that includes the lifelong accumulation of molecular damage, leading to age-related frailty, disability and disease, and eventually death. In this study, we report evidence of a significant correlation between the number
Fu, Xiaoming, Gagneux, Pascal, Garcia, Javier O, Garcia-Bingman, Andrea, Glass, Christopher K, Hazen, Stanley L, Heyser, Charles, Lin, Hongqiao, Läubli, Heinz, Pearce, Oliver MT, Romanoski, Casey E, Samraj, Annie N, Schwarz, Flavio, Secrest, Patrick, Varki, Ajit, Varki, Nissi, Wang, Xiaoxia   +16 more
core   +1 more source

Oxidative DNA damage accumulation in gastric carcinogenesis [PDF]

Gut, 1998
Background—Gastric carcinogenesis is a multifactorial, multistep process, in which chronic inflammation plays a major role.Aims—In order to ascertain whether free radical mediated oxidative DNA damage is involved in such a process, concentrations of 8-hydroxydeoxyguanosine (8OHdG), a mutagenic/carcinogenic adduct, and thiobarbituric acid reactive ...
FARINATI, FABIO, CARDIN, ROMILDA, DEGAN P, RUGGE, MASSIMO, DI MARIO F, BONVICINI P, NACCARATO R.   +6 more
openaire   +3 more sources

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Study on Hysteresis Model of Welding Material in Unstiffened Welded Joints of Steel Tubular Truss Structure

Applied Sciences, 2018
The weld form of intersecting joints in a steel tubular truss structure changes with the various intersecting curves. As the key role of joints in energy dissipation and seismic resistance, the weld is easy to damage, as a result the constitutive ...
Yaqi Suo, Wenwei Yang, Peng Chen
doaj   +1 more source