Results 191 to 200 of about 1,392,331 (344)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Cyclin dependent kinase 9 inhibitor induces transcription-replication conflicts and DNA damage accumulation in breast cancer. [PDF]

Cancer Cell Int
Lee M, Lee KH, Min A, Kim SH, Ham S, Hwang HM, Noh Y, Kim YJ, Lee DW, Koh J, Im SA.   +10 more
europepmc   +1 more source

Damage accumulation mechanism in PIN diode limiters induced via multiple microwave pulses. [PDF]

Sci Rep, 2020
Zhao J, Chen Q, Zhao G, Chen C, Chen Z.
europepmc   +1 more source

Pre-treatment With Fasudil Prevents Neomycin-Induced Hair Cell Damage by Reducing the Accumulation of Reactive Oxygen Species

, 2019
Yanqiu Zhang, Wei Li, Zuhong He, Yunfeng Wang, Buwei Shao, Cheng Cheng, Shasha Zhang, Mingliang Tang, Xiaoyun Qian, Weijia Kong, Hui Wang, Renjie Chai, Xia Gao   +12 more
openalex   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

<i>Dicer1</i> Depletion Leads to DNA Damage Accumulation and Cell Death in a RET/PTC3 Papillary Thyroid Cancer Mouse Model, Thereby Inhibiting Tumor Progression. [PDF]

Cells
Rojo-Pardillo M, Augenlicht A, Dom G, Kero J, Robaye B, Maenhaut C.   +5 more
europepmc   +1 more source

Gaidai multimodal risk evaluation methodology based on cargo vessel onboard measurements, given structural damage accumulation [PDF]

Oleg Gaidai, Alia Ashraf, Yu Cao, Jinlu Sheng, Hongchen Li, Zirui Liu, Yan Zhu   +6 more
openalex   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Numerical Simulation of Rubber Concrete Considering Fatigue Damage Accumulation of Cohesive Zone Model. [PDF]

Materials (Basel)
Liu C, Li H, Min K, Li W, Wu K.
europepmc   +1 more source

Theoretical Forecasting and Experimental Validation of Damage Tolerance and Accumulation in Glass/Epoxy Laminates [PDF]

, 1992
Nicola Bonora, M. Marchetti, Pietro Paolo Milella   +2 more
openalex   +1 more source