Results 91 to 100 of about 3,928,621 (275)

Correlating low energy impact damage with changes in modal parameters: a preliminary study on composite beams [PDF]

open access: yes, 2009
This paper is an experimental study of the effects of multi-site damage on the vibration response of a composite beam damaged by low energy impact. The variation of the modal parameters with different levels of impact energy and density of impact is ...
Morlier, Joseph   +2 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Microgels and apparatus for PAGE of nucleic acids in one or two dimensions

open access: yesBioTechniques, 2018
We describe a system for horizontal 1D or 2D PAGE comprising an apparatus and microgels. There is no buffer outside the gel, making handling and sample loading easy.
Hans G Thormar   +5 more
doaj   +1 more source

A General Bayesian Framework for Ellipse-based and Hyperbola-based Damage Localisation in Anisotropic Composite Plates [PDF]

open access: yes, 2015
This paper focuses on Bayesian Lamb wave-based damage localization in structural health monitoring of anisotropic composite materials. A Bayesian framework is applied to take account for uncertainties from experimental time-of-flight measurements and ...
GUSKOV, Mikhail   +3 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Deep Autoencoder Framework for Classifying Damage Mechanisms in Repaired CFRP

open access: yesApplied Sciences
This study investigates the classification of damage modes in adhesively bonded carbon fiber-reinforced plastic (CFRP) composites, a critical factor in advancing lightweight automotive design.
Claudia Barile   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Characterization of the EBV-Induced Persistent DNA Damage Response

open access: yesViruses, 2017
Epstein-Barr virus (EBV) is an oncogenic herpesvirus that is ubiquitous in the human population. Early after EBV infection in vitro, primary human B cells undergo a transient period of hyper-proliferation, which results in replicative stress and DNA ...
Amy Y. Hafez, Micah A. Luftig
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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