Results 81 to 90 of about 3,928,621 (275)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Multi-Dimensional AE Signal Features in Eccentrically Loaded Concrete Structures: A Machine Learning Classification for Damage Progression

Applied Sciences
Acoustic emission (AE) signals exhibit a strong correlation with concrete damage. However, the relationship between column damage and AE signals under eccentric loading conditions, combined with the application of traditional RA-AF classification methods
Shilong Ding, Alipujiang Jierula, Abudusaimaiti Kali, Tong Han, Tae-Min Oh   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An Approach to Acoustic Emission Technique Applications to Evaluate Damage Mechanisms in Composite Materials

MATEC Web of Conferences, 2015
Acoustic Emission technique is a versatile method for characterization in materials science. It is considered to be a “passive” non-destructive method since damage can be only evaluated when de defects are being developed during the test which, at the ...
Rios-Soberanis C.R.
doaj   +1 more source

The influence of toughening-particles in CFRPs on low velocity impact damage resistance performance [PDF]

, 2014
The role of particle-toughening for increasing impact damage resistance in carbon fibre reinforced polymer (CFRP) composites was investigated. Five carbon fibre reinforced systems consisting of four particle-toughened matrices and one system containing ...
D.J. Bull, Scott, A.E., I. Sinclair, Bull, D.J., Spearing, S.M., A.E. Scott, Sinclair, I., S.M. Spearing   +7 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Correlating low energy impact damage with changes in modal parameters: diagnosis tools and FE validation [PDF]

, 2010
This paper presents a basic experimental technique and simplified FE based models for the detection, localization and quantification of impact damage in composite beams around the BVID level.
Niemann, Hanno, Joseph Morlier, Morlier, Joseph, Gourinat, Yves, Hanno Niemann, Shahdin, Amir, Yves Gourinat, Amir Shahdin   +7 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Characterization of radiation damage to DNA by reaction with borohydride

Nucleic Acids Research, 1981
Irradiation of aqueous solutions of native calf thymus DNA with x-rays produced functional groups that reacted with sodium borohydride. The DNA was labeled with tritium from NaB3H4 to the extent of 2.0 x 10(-10) atom/dalton/rad. The presence of cysteamine or other radical scavengers, or saturation of the solution with nitrogen during irradiation ...
K A, Schellenberg, J, Shaeffer, R K, Nichols, D, Gates   +3 more
openaire   +3 more sources