Results 121 to 130 of about 3,928,621 (275)

Damage location method for thin composites structures - application to an aircraft door [PDF]

open access: yes, 2013
Piezoelectric sensors are widely used for Structure Health Monitoring (SHM) technique due to their high-frequency capability. In particular, electromechanical impedance (EMI) techniques give simple and low cost solutions for detecting damage in composite
Pommier-Budinger, Valérie   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Structural health monitoring using the Firefly optimization algorithm and finite elements

open access: yesRevista UIS Ingenierías, 2020
In this study, a novel technique for multiple damage detection of structures using modal characterization to evaluate the dynamic response of the structure given a damage model is investigated. The damage identification problem is seen as an optimization
Octavio Andrés González-Estrada   +2 more
doaj  

Damage mechanics and fatigue life assessment of composite materials

open access: yes, 1999
The present state of fatigue life assessment of composite materials is largely empirical. This paper discusses how the discipline of damage mechanics can elevate this status to a mechanisms-based methodology.
Talreja, Ramesh
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Damage Tolerant Active Contro l: Concept and State of the Art [PDF]

open access: yes, 2012
Damage tolerant active control is a new research area relating to fault tolerant control design applied to mechanical structures. It encompasses several techniques already used to design controllers and to detect and to diagnose faults, as well to ...
NOBREGA, Euripedes, MECHBAL, Nazih
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Histopathological characterization of photochemical damage in nervous tissue.

open access: yesHistology and histopathology, 1994
This paper discusses histological and ultrastructural changes produced by dye-sensitized photoreactions in the central and peripheral nervous system. Particular attention has been given to morphological outcome in experimental models which reproduce widespread clinical pathologies, e.g. stroke, spinal cord injury and peripheral neuropathy.
Van Reempts, J., Borgers, M.
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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