Results 121 to 130 of about 8,161,887 (352)

Underlying modal data issues for detecting damage in truss structures [PDF]

open access: yes
Independent of the modal identification techniques employed for damage detection, use of measured modal data limits the expectations for damage location.
Kashangaki, Thomas A-L.   +2 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Research on Bridge Integrity Assessment and Early Warning Monitoring Methods Based on Bearing Reaction Force

open access: yesBuildings
Traditional bridge monitoring and damage identification techniques typically rely on full-bridge coverage of sensors, such as displacement or strain sensors.
Shu Li   +4 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Enhancing the Damage Detection and Classification of Unknown Classes with a Hybrid Supervised–Unsupervised Approach

open access: yesInfrastructures
Most damage-assessment strategies for dynamic systems only distinguish between undamaged and damaged conditions without recognizing the level or type of damage or considering unseen conditions.
Lorenzo Stagi   +7 more
doaj   +1 more source

Detecting Damage in Composites [PDF]

open access: yesMechanical Engineering, 1998
Research shows that polarimetric optical-fiber sensors embedded in composite laminates can monitor structural integrity and detect damage while the structure remains in service. An experimental arrangement can be created to monitor strain in composite specimens.
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Trend Decomposition for Temperature Compensation in a Radar-Based Structural Health Monitoring System of Wind Turbine Blades

open access: yesSensors
The compensation of temperature is critical in every structural health monitoring (SHM) system for achieving maximum damage detection performance. This paper analyses a novel approach based on seasonal trend decomposition to eliminate the temperature ...
Jonas Simon, Jochen Moll, Viktor Krozer
doaj   +1 more source

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