Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Identification of constututive parameters by using fuill-field measurements: an example of application to an elastoplastic damage model = Identificação de parâmetros constitutivos baseada na medição de campos de deslocamentos : exemplo de aplicação para um modelo de dano elastoplástico [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia MecânicaA identificação de parâmetros constitutivos é usualmente realizada através da minimização de uma função objetivo, função ...
Castro, Paulo Bastos de
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This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Perturbation Analysis for Robust Damage Detection with Application to Multifunctional Aircraft Structures [PDF]
The most widely known form of multifunctional aircraft structure is smart structures for structural health monitoring (SHM). The aim is to provide automated systems whose purposes are to identify and to characterize possible damage within structures by ...
HAJRYA, Rafik, MECHBAL, Nazih
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Application of Phase Space Warping on Damage Tracking for Bearing Fault
Nowadays, the significance of keeping equipment function properly each time is obvious. If equipment fails during its use, it may have disastrous consequences.
Gu, Fengshou +3 more
core +1 more source
Wavelet transform-based damage identification in laminated composite beams [PDF]
Laminated composite structures suffers from delamination, the detachment of the layers due to the rupture of the fiber-matrix interface, as their principal mode of failure.
OLIVER, Guilherme Antonio
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An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Sub-surface damage location and identification using infra-red techniques
The paper presents a new methodology for identifying sub-surface damage in composite components using a combination of Pulse Phase Thermography (PPT) and Thermoelastic Stress Analysis (TSA)
Cunningham, P.R. +2 more
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