Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Evaluation of the esthetic properties of developmental defects of enamel: a spectrophotometric clinical study [PDF]
Objectives. Detailed clinical quantification of optical properties of developmental defect of enamel is possible with spectropho- tometric evaluation. Developmental defects of enamel (DDE) are daily encountered in clinical practice. DDE are an alteration
Corridore, Denise +5 more
core +4 more sources
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
An evaluating methodology for hydrotechnical torrent-control structures condition [PDF]
Watershed management using torrent-control structures is an activity having more than 100 years history in Romania, So far, researches regarding works behaviour in service focused mainly on defining and assessing each damage type, without studying the ...
Şerban Octavian Davidescu +3 more
doaj
Seismic damage analysis including inelastic shear-flexure interaction [PDF]
The paper focusses on seismic damage analysis of reinforced concrete (R/C) members, accounting for shear-flexure interaction in the inelastic range. A finite element of the beam-column type for the seismic analysis of R/C structures is first briefly ...
Kappos, A. J., Mergos, P.E.
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Early damage index in systemic lupus erythematosus
Objective. To characterize early damage index (EDI) and prove its usefulness for prognosis of systemic lupus erythematosus (SLE) outcome. Material and methods.
I A Andrianova, M M Ivanova
doaj +1 more source
A new damage index for plane steel frames exhibiting strength and stiffness degradation under seismic motion [PDF]
A new damage index for plane steel frames under earthquake ground motion is proposed. This index is defined at a section of a steel member and takes into account the interaction between the axial force N and bending moment M acting there.
Beskos, DE +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Vibration based Structural Health Monitoring of a Composite Plate Structure with Multiple Stiffeners [PDF]
A vibration based damage identification method is investigated experimentally.\ud The dynamic response of an intact and a locally damaged 16–layer unidirectional\ud carbon fibre PEKK reinforced plate structure with two stiffener sections is considered ...
Akkerman, R. +4 more
core +2 more sources

