A domain damage index to prioritizing the pathogenicity of missense variants. [PDF]
Hum Mutat, 2021 Chen HC, Wang J, Wang J, Liu Q, Shyr Y.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Vibration-Based Damage Detection in Plate Structure without Baseline Modal Parameters
In this paper an on-going research effort aimed at detecting and localizing damage in plate-like structures by using a mode shape curvature based damage detection method is described.
Ručevskis, Sandris +2 more
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Early renal damage assessed by the SLICC/ACR damage index is predictor of severe outcome in lupus patients in Pakistan [PDF]
, 2010 We investigated Patients with systemic lupus erythematosus with the objective of assessing whether early damage accrued in systemic lupus erythematosus as measured by the SLICC/ACR Damage Index predicts mortality in lupus Patients that have been followed
Shah, S. M. A. +7 more
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Association between SLICC/ACR damage index and outcomes for lupus patients after cardiac valve surgery. [PDF]
Interact Cardiovasc Thorac Surg, 2022 Hu SY +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Circulating irisin levels in functional hypothalamic amenorrhea: a new bone damage index? A pilot study. [PDF]
Endocrine, 2022 Notaristefano G +13 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
OF THE H-INDEX AND ITS ALTERNATIVES: AN APPLICATION TO THE 100 MOST PROLIFIC ECONOMISTS [PDF]
The h-index is a recent but already quite popular way of measuring research quality and quantity. However, it discounts highly-cited papers. The g-index corrects for this, but it is sensitivity to the number of never-cited papers.
Richard S.J. Tol
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source