Results 151 to 160 of about 5,763,068 (274)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A novel integrated framework for damage detection in steel structures using magnetic piezoelectric sensors and hybrid damage index. [PDF]

Sci Rep
Aulakh DS, Rawat D, Bhalla S.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Cardiovascular risk scores, non-invasive vascular measures and myositis damage index reveal increased cardiovascular risk in idiopathic inflammatory myopathies: a case-control study. [PDF]

BMC Rheumatol
Garcia-Ordoñez GP, Ramos-Becerra CG, Corona-Meraz FI, Salazar-Paramo M, Perez-Vazquez F, Quirarte-Tovar EF, Juarez-Gomez C, Aguilar-Vazquez A, Vazquez-Del Mercado M.   +8 more
europepmc   +1 more source

THE EXCRETION OF XYLOSE AS AN INDEX OF DAMAGED RENAL FUNCTION [PDF]

Journal of Clinical Investigation, 1932
E H, Fishberg, L, Friedfeld
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Behçet's Syndrome Overall Damage Index performance and validation in an adult Egyptian cohort. [PDF]

Arch Rheumatol
Attia D, Maged L.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Application of the Scleroderma Clinical Trials Consortium Damage Index in patients with juvenile systemic sclerosis. [PDF]

Pediatr Rheumatol Online J
Zhang C, Wang C, Gao S, Ma M, Wang W, Zhang T, Zhang Y, Tang X, Li Z, Sun Z, Wang L, Jin H, Zeng X, Song H.   +13 more
europepmc   +1 more source

Anti-Sm Antibody, Damage Index, and Corticosteroid Use Are Associated with Cardiac Involvement in Systemic Lupus Erythematosus: Data from a Prospective Registry Study. [PDF]

J Korean Med Sci, 2020
Choe JY, Lee SS, Kwak SG, Kim SK.
europepmc   +1 more source