Results 251 to 260 of about 759,222 (305)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

No benefit of adding glucocorticoids to maintenance treatment in reducing the risk of major relapses in ANCA-associated vasculitis: real life data from a longitudinal cohort study. [PDF]

open access: yesRMD Open
Chavatza K   +16 more
europepmc   +1 more source

Extent and Progression of Cardiac Damage in Patients With Primary Mitral Regurgitation Undergoing Surgical Repair. [PDF]

open access: yesEur J Cardiothorac Surg
Myagmardorj R   +16 more
europepmc   +1 more source

Application of the modified damage index method to timber beams [PDF]

open access: yesEngineering Structures, 2008
In this paper the use of two existing algorithms developed for global nondestructive evaluation to locate and evaluate localised damage in timber beams is investigated using a finite element model. These damage localisation algorithms were found, through
Jianchun Li, B Samali, Keith Crews
exaly   +2 more sources

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