Results 101 to 110 of about 958,470 (300)
Mussel eggs as indicators of mutagen exposure in coastal and estuarine environments [PDF]
The aim of this study was to develop a short-term genotoxicity assay for monitoring the marine environment for mutagens. Based on the developing eggs and embryos of the marine mussel Mytilus edulis, an important pollution indicator species, the test ...
Dixon, D.R., Pascoe, P.L
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
This article presents the results of an experimental campaign conducted on a set of four unreinforced masonry walls at full scale. The purpose of this study is to assess, using non-destructive methods, the impact of retrofitting and damage on the modal ...
Joaquín Romero-Carrasco +2 more
doaj +1 more source
Modeshapes recognition using Fourier descriptors: a simple SHM example [PDF]
The main objective of this study is to develop an alternative criterion for modeshape classification, as the currently available one, MAC (Modal Assurance Criteria), is only a vector correlation representing modeshape similarities.
Bergh, Mauricio +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Nox2 redox signaling maintains essential cell populations in the brain. [PDF]
Reactive oxygen species (ROS) are conventionally classified as toxic consequences of aerobic life, and the brain is particularly susceptible to ROS-induced oxidative stress and damage owing to its high energy and oxygen demands.
Chang, Christopher J +4 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Fatigue response of notched laminates subjected to tension-compression cyclic loads [PDF]
The fatigue response of a ((0/45/90/-45)(sub s))(sub 4) T300-5208 graphite-epoxy laminate with a drilled center-hole subjected to various components of tensile and compressive cyclic loads was investigated.
Bakis, C. E., Stinchcomb, W. W.
core +1 more source
Multi-phase materials are key for modern engineering applications. They are generally characterized by a high strength and ductility. Many of these materials fail by ductile fracture of the, generally softer, matrix phase.
de Geus, T. W. J. +2 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

