Results 111 to 120 of about 958,470 (300)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Photoelectrochemical Sensors for the Rapid Detection of DNA Damage Induced by Some Nanoparticles [PDF]

open access: yesPakistan Journal of Analytical & Environmental Chemistry, 2010
Photoelectrochemcal sensors were developed for the rapid detection of oxidative DNA damage induced by titanium dioxide and polystyrene nanoparticles. Each sensor is a multilayer film prepared on a tin oxide nanoparticle electrode using layer- by-layer ...
M. Jamaluddin Ahmed   +2 more
doaj  

The impact of climate change on hurricane damages in the United States [PDF]

open access: yes
This paper quantifies hurricane damage caused by climate change across the US. A damage function is estimated from historic hurricane data to measure the impacts at each location given the storm's strength.
Chonabayashi, Shun   +2 more
core  

A survey on the possibility of utilizing γH2AX as a biodosimeter in radiation workers [PDF]

open access: yes, 2015
Introduction DNA damage is among the main consequences of radiation. Of many different classes of DNA damage, double-strand breaks are the most deleterious.
Asadi, J.   +3 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Study on Seismic Safety Evaluation Models for Gravity Dams Based on Integrated Performance Indicators

open access: yesRenmin Zhujiang
Existing studies typically explore the differences in seismic performance evaluation results of different evaluation models for concrete gravity dams by analyzing amplitude factors while neglecting the influence of ground motion duration.
FAN Wenzhan, ZHU Shaokun, CHEN Bo
doaj   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Creatine kinaza as transient muscular damage indicator: Analyzes and importance for technology of sports training [PDF]

open access: yesFizička Kultura, 2018
Previous research suggests that there is no single marker that would be sufficiently reliable indicator of muscle damage and overtraining. Monitoring several physiological indicators can lead to the desired response.
Marić Bojana
doaj  

Is Australia on a sustainability path? Interpreting the clues [PDF]

open access: yes
Genuine savings is a conceptually valid one-sided indicator as to whether Australia is on a weak sustainability path (negative GS would warn that current welfare is unsustainable).
Randall, Alan
core   +1 more source

Home - About - Disclaimer - Privacy