NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Role of cystatin C in predicting the risk of hypermethotrexemia and kidney injury after high-dose methotrexate chemotherapy in childhood acute lymphoblastic leukemia. [PDF]
Pei W +10 more
europepmc +1 more source
Determination of an indicator for the devaluation of houses caused by earthquakes in Groningen:A secondary analysis of the relationship between physical indicators and reported damage, and a pragmatic method for estimating the devaluation calculating for calculation of [PDF]
de Kam, George, Hol, Eric
openalex
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Application of Multi-Sensor Data Fusion and Machine Learning for Early Warning of Cambrian Limestone Water Hazards. [PDF]
Li H, Li Y, Lin W, Yang H, Liu K.
europepmc +1 more source
APPLICATION OF NEW DAMAGE INDICATOR-BASED SEQUENTIAL LAW TO ESTIMATE FATIGUE LIFE OF OFFSHORE JACKET STRUCTURES [PDF]
Redion Kajolli +2 more
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Time-dependent 53BP1 foci kinetics in X-irradiated human hair follicle dermal papilla cells. [PDF]
Hanamiya D, Etani R, Ojima M.
europepmc +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source

