Results 81 to 90 of about 852,434 (310)

Fatigue indicators for metal structures: from aircraft to bridges

Aviation
The papers focus on a fatigue monitoring method for two types of engineering structures: (a) aircraft and (b) steel bridges. However, the potential application of this new approach extends beyond these examples.
Mykhailo Karuskevych, Tetiana Maslak, Oleg Karuskevych, Yurii Vlasenko   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Linking Weak and Strong Sustainability Indicators: The Case of Global Warming [PDF]

The aim of this paper is to describe and discuss the weak and strong sustainability approach of assessing climate change and to show reasonable applications, weaknesses, possible improvements and linkages of both approaches. Main features of ?weak?
Hohmeyer, Olav, Rennings, Klaus
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Investigating inter-turn fault in transformer using TTR and FRA [PDF]

, 2019
Transformers are one of the significant elements in the power system network. The Transformer function is to step up and down the voltages. When the transformer operating in high load, it exposes to failures.
Abdulrazzaq Al-Iedani, Ali Salman
core  

Microborings in mid Cretaceous fish teeth [PDF]

, 1999
Fish teeth and other remains from the British Cretaceous contain abundant evidence for post-mortem colonization by endolithic organisms. The borings are here recognised as occurring in three morphotypes, including a flask-shaped form not previously ...
Brett, Bystrov, C. J. Underwood, C. J. Veltkamp, Ennis, Gouget, Martill, Mitchell, Mägdefrau, Owen, S. F. Mitchell, Siverson, Tavernier, Vogel   +13 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Cross-Disciplinary Analysis of the On-Farm Transition from Conventional to Organic Vegetable Production [PDF]

, 2008
This farm-scale analysis of the three-year transition to organic from conventional vegetable production tracked the changes in crop, soil, pest and management on two ranches (40 and 47 ha) in the Salinas Valley, California.
Jackson, Louise E., Koike, Steve, Murphree, Liese, Smith, Richard, Smukler, Sean M., Yokota, Ron   +5 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Need for Environmental Indicators Coverage. The Ecological Footprint

EIRP Proceedings, 2016
Our paper's aim is to review some of the most relevant indicators describing the environmental damage and to affirm the need of better understanding and evaluating it.
Florian Nuta
doaj