Results 181 to 190 of about 436,032 (358)

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Some Micromechanical Aspects of Damage and Fracture

Acta Polytechnica, 2000
The failure mode is described by means of elasto-plastic fracture mechanics and the main aspects of fatigue crack behaviour are itemized. The crux of the matter is the presentation of the pplicability limits of the three substantially different fatigue ...
P. Brož
doaj  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Análisis de las causas y efectos de la avería de compresor de amoniaco en Frigorífico de la ciudad de Cienfuegos. // Analysis of causes and effects for failure in ammonia compressor.

Ingeniería Mecánica, 2002
En el artículo se analizan las causas de una avería producida en un compresor de amoniaco del Frigorífico de la ciudad deCienfuegos. En el trabajo se aplican los conceptos de la Fractura Mecánica Lineal Elástica y de la Fractura MecánicaSubcrítica para ...
R. Goytisolo Espinosa, N. Arzola de la Peña, L. Martínez Díaz, L. Bruno Wason, T. Frómeta Castillo, J. J. Cabello Eras   +5 more
doaj  

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Multiaxial Fatigue Life Assessment of Large Welded Flange Shafts: A Continuum Damage Mechanics Approach. [PDF]

Materials (Basel)
Xu Z, Yang C, Shi F, Liu W, Xu N, Hu Z, Li C, Liu K, Cao P, Wang D.   +9 more
europepmc   +1 more source

An experimentally-calibrated damage mechanics model for stone fracture in shock wave lithotripsy. [PDF]

Int J Fract, 2018
Fovargue D, Mitran S, Sankin G, Zhang Y, Zhong P.   +4 more
europepmc   +1 more source

Continuum damage mechanics models and their applications to composite components of aero-engines [PDF]

, 2016
Tianhong Yu
openalex  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Fatigue Life Analysis of Titanium Torsion Spring Based on Continuous Damage Mechanics. [PDF]

Materials (Basel)
Meng D, Zhang C, Yang F, Duan F.
europepmc   +1 more source