Results 161 to 170 of about 2,598,216 (300)

Damage Mechanism of HgCdTe Focal Plane Array Detector Irradiated Using Mid-Infrared Pulse Laser. [PDF]

Sensors (Basel), 2023
Zhang Y, Zheng C, Liu Y, Wang Y, Xu Y, Shao J.   +5 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Damage Mechanism and Modeling of CFRP Laminates Impacted by Single Waterjets: Effect of the Impact Direction. [PDF]

Materials (Basel)
Hou N, Li Y, Liu P.
europepmc   +1 more source

In vitro investigation of stone ablation efficiency, char formation, spark generation, and damage mechanism produced by thulium fiber laser. [PDF]

Urolithiasis, 2023
Chen J, Mishra A, Medairos R, Antonelli J, Preminger GM, Lipkin ME, Zhong P.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Study on Damage Mechanism of Fiber Concrete with Initial Pores. [PDF]

Materials (Basel)
Hu A, Du X, Wang F, Li J, Zhang T, Li Y.
europepmc   +1 more source

Pyroptosis-Mediated Damage Mechanism by Deoxynivalenol in Porcine Small Intestinal Epithelial Cells. [PDF]

Toxins (Basel), 2023
Kang TH, Shin S, Park J, Lee BR, Lee SI.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Damage Mechanism Analysis of High Field Stress on Cascode GaN HEMT Power Devices. [PDF]

Micromachines (Basel)
Su S, Cao Y, Zhang W, Zhang X, Chen C, Wu L, Zhang Z, Li M, Lv L, Zheng X, Tian W, Ma X, Hao Y.   +12 more
europepmc   +1 more source

Freeze-Thaw Damage Mechanism Analysis of SBS Asphalt Mixture Containing Basalt Fiber and Lignocellulosic Fiber Based on Microscopic Void Characteristics. [PDF]

Polymers (Basel), 2023
Wang W, Yang L, Cui H, Wu F, Cheng Y, Liang C.   +5 more
europepmc   +1 more source