Results 181 to 190 of about 2,598,216 (300)

Shock-Induced Damage Mechanism of Perineuronal Nets. [PDF]

Biomolecules, 2021
Mahmud KAHA, Hasan F, Khan MI, Adnan A.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Research on the mechanical properties and micro damage mechanism of water bearing sandstone under uniaxial compression. [PDF]

Sci Rep
Liu K, Zhao S, Diao L, Yue W, Sun C, Xia Y.   +5 more
europepmc   +1 more source

Formation-Damage Mechanism and Gel-Breaker-Free Drill-In Fluid for Carbonate Reservoir. [PDF]

Gels, 2022
Fang Q, Zhao X, Sun H, Wang Z, Qiu Z, Shan K, Ren X.   +6 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Radiation-induced skin reactions: oxidative damage mechanism and antioxidant protection. [PDF]

Front Cell Dev Biol
Liu C, Wei J, Wang X, Zhao Q, Lv J, Tan Z, Xin Y, Jiang X.   +7 more
europepmc   +1 more source

Study on the Cutting Damage Mechanism of Aramid Honeycomb Based on the Progressive Damage Model. [PDF]

Materials (Basel), 2022
Yang Y, Bao Y, Wang J, Chen C.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Microstructure Evolution and Damage Mechanism of DD9 Single Crystal Superalloy-Thermal Barrier Coating System Under High Temperature Oxidation: A Comparative Study with DD6. [PDF]

Materials (Basel)
Li P, Xin Z, Sun F, Jin X, Zhang C.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source