Results 71 to 80 of about 2,596,701 (301)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Biodamage via shock waves initiated by irradiation with ions [PDF]
, 2013 Radiation damage following the ionising radiation of tissue has different scenarios and mechanisms depending on the projectiles or radiation modality. We investigate the radiation damage effects due to shock waves produced by ions.
Solov'yov, Andrey V. +2 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Microstructure and fatigue damage mechanism of 6082-T6 aluminium alloy welded joint
Materials Research Express, 2021 In this paper, 6mm thick 6082-T6 high-strength aluminium alloy is taken as the research object, and CLOOS ROMAT-3500 industrial robot MIG welder is used for welding.
Minqi Zhu +3 more
doaj +1 more source
Nickel Carcinogenesis Mechanism: DNA Damage [PDF]
International Journal of Molecular Sciences, 2019 Nickel (Ni) is known to be a major carcinogenic heavy metal. Occupational and environmental exposure to Ni has been implicated in human lung and nasal cancers. Currently, the molecular mechanisms of Ni carcinogenicity remain unclear, but studies have shown that Ni-caused DNA damage is an important carcinogenic mechanism.
Hongrui Guo +9 more
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Applied Sciences, 2018 Understanding the tensile failure mechanisms in carbon fiber woven composites based on the acoustic emission (AE) technique is a challenging task.
Wei Zhou, Peng-fei Zhang, Yan-nan Zhang
doaj +1 more source
Study on flexural properties of coal gangue powder asphalt mixture under freeze-thaw cycles
Materials Research Express, 2022 In order to study the influence of freeze-thaw cycle on the flexural performance of asphalt pavement, semi-circular flexural test (SCB) is carried out.
Jinrong Wu +3 more
doaj +1 more source
, 2012 The anticipated performance of calorimeter crystals in the environment expected after the planned High-Luminosity upgrade of the Large Hadron Collider (HL-LHC) at CERN has to be well understood, before informed decisions can be made on the need for ...
Dissertori, G. +7 more
core +2 more sources
Corrosion Damages Induced by Cyclic Exposure of 2024 Aluminum Alloy in Chloride-Containing Environments [PDF]
, 2011 This paper focuses on the influence of cyclic exposure to chloride solutions on corrosion damage morphology developed on AA2024. The influence of the temperature during the air exposure periods was studied.
Alexis, Joël +5 more
core +2 more sources