Results 51 to 60 of about 351,149 (262)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Hydroxymethylfurfural: an indicative parameter of heat damage in cereal products
Czech Journal of Food Sciences, 2004 The main chemical changes occurring during biscuit cooking result from two complex reactions involving reducing sugars: the Maillard reaction and caramelisation, both of them being responsible for non enzymatic browning.
L. Ait Ameur +3 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Applied MechanicsAluminium alloys are used for the fabrication of the fuel clad of research-grade nuclear reactors as well as for several types of core components of high-flux research reactors.
Mahendra Kumar Samal +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A Damage Detection Strategy Based on Autoregressive Parameters
Structural Health Monitoring (SHM) based on Operational Modal Analysis (OMA) is pivotal in assessing the integrity of structures and infrastructures in dynamic regimes. However, the successful extraction of modal parameters and damage indexes through OMA typically relies on a dense network of sensors working synchronously.
M. A. Siddiqui +4 more
openaire +1 more source
A Proposal of Grain Boundary Damage Parameter.
Journal of the Society of Materials Science, Japan, 1995 A new grain boundary damage parameter, D-parameter, is proposed to evaluate grain boundaries damaged and to estimate the remaining life of components under creep loading at high temperature. This method is significantly different from the others firstly by specifying the grain boundaries normal to the principal stress direction in the area and secondly
KIKUCHI, Kenji, KAJI, Yoshiyuki
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source