Results 161 to 170 of about 1,289,857 (204)

Dynamic recognition and repair of DNA complex damage

Journal of Cellular Physiology, 2018
AbstractIrradiation (IR) can be used to treat cancer by inducing complex and irreparable DNA damage in the cancer cells, which may lead to their apoptotic death. However, little is known about the molecular mechanism of this DNA damage. Here, the non‐small‐cell lung cancer cell line A549 was treated with either X‐ray or carbon ion combined with ...
Junfang Yan, Yi Xie, Qianjing Zhang, Lu Gan, Fang Wang, Hongyan Li, Jing Si, Hong Zhang   +7 more
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DNA repair: models for damage and mismatch recognition

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2000
Maintaining the integrity of the genome is critical for the survival of any organism. To achieve this, many families of enzymatic repair systems which recognize and repair DNA damage have evolved. Perhaps most intriguing about the workings of these repair systems is the actual damage recognition process.
Rajski, Scott R., Jackson, Brian A., Barton, Jacqueline K.   +2 more
openaire   +3 more sources

Intact recognition of emotional prosody following amygdala damage

Neuropsychologia, 1999
Bilateral damage to the amygdala in a variety of animal species can impair emotional reactions to stimuli in several sensory modalities. Such damage in humans impairs visual recognition of emotion in facial expressions, but possible impairments in modalities other than vision have not been sufficiently explored.
R, Adolphs, D, Tranel
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Action recognition disorders following parietal damage

2006
Abstract From the moment of our birth, we act in the world. Despite such a large motor experience, we have a poor subjective knowledge of the entire set of processes that underlie our motor skills. Interestingly, even if we remain largely unaware of the contents of our actions, we are usually good at judging whether an action has ...
Elena Daprati, Angela Sirigu
openaire   +1 more source

Recognition of random shapes in brain-damaged patients

European Archives of Psychiatry and Neurological Sciences, 1987
In two experiments the hypothesis was tested that left hemisphere-damaged patients and especially those with aphasia are impaired in the recognition of meaningless random shapes because they fail to attribute a meaning to the shapes. In a multiple choice recognition task, left hemisphere-damaged patients with aphasia and left and right hemisphere ...
A, Glöckner-Rist, K, Gutbrod, R, Cohen
openaire   +2 more sources

Recognition of damage in polarizing transmission-grating facets

Applied Optics, 1996
An optical setup was built for microscopic damage inspection on transmission-grating facets composed of a gold-wire structure. Contrast improvement was achieved by exploiting the polarizing properties of these gratings in the near-infrared region. Spatial filtering yields an additional contrast enhancement and reduces unwanted signals caused by the ...
H, Lochbihler, C, Rotsch, P, Predehl
openaire   +2 more sources

Damage recognition in nucleotide excision repair of DNA

Gene, 2000
Nucleotide excision repair (NER) is found throughout nature, in eubacteria, eukaryotes and archaea. In human cells it is the main pathway for the removal of damage caused by UV light, but it also acts on a wide variety of other bulky helix-distorting lesions caused by chemical mutagens.
D P, Batty, R D, Wood
openaire   +2 more sources

Fear recognition deficits after focal brain damage

Neurology, 2000
To test the hypothesis that fear recognition deficits in neurologic patients reflect damage to an emotion-specific neural network.Previous studies have suggested that the perception of fear in facial expressions is mediated by a specialized neural system that includes the amygdala and certain posterior right-hemisphere cortical regions.
S Z, Rapcsak, S R, Galper, J F, Comer, S L, Reminger, L, Nielsen, A W, Kaszniak, M, Verfaellie, J F, Laguna, D M, Labiner, R A, Cohen   +9 more
openaire   +2 more sources

Structural Damage Localization Using Element Signature Recognition

AIAA Journal, 2007
In damage detection algorithms the use of mode-force error arising from reduced analytical system matrices precludes the possibility of stiffness damage localization for those elements residing entirely outside the analysis set. Subsequently, any indication of mode-force error arising from damage appears as a force imbalance in each reduced degree of ...
Frank P. Lopez, David C. Zimmerman
openaire   +1 more source

Intragenomic Hierarchies of DNA Damage Recognition

1997
Nuclear DNA in mammalian cells is a highly nonuniform substrate with respect to its susceptibility to genotoxic reactions. For example, cyclobutane pyrimidine dimer formation is modulated at the nucleosomal level with a 10.3 base average periodicity.1,2 The frequency of pyrimidine(6-4)pyrimidone photoproducts is greater in nuclease-sensitive DNA than ...
openaire   +1 more source