Results 41 to 50 of about 600,627 (295)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sensors, 2023 Deep learning models have been widely used in data-driven bridge structural damage diagnosis methods in recent years. However, these methods require training and test datasets to satisfy the same distribution, which is difficult to satisfy in practice ...
Haitao Xiao +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Rapid Damage Scenario Assessment for Earthquake Emergency Management
Seismological Research Letters, 2021 AbstractThe rapid availability of reliable damage statistics, after the occurrence of a major earthquake, is an essential mitigation strategy to drive and support emergency intervention operations. Unfortunately, the latency in collecting and organizing actual damage information has a substantial impact on the efficiency of the initial phases of the ...
Poggi V +6 more
openaire +2 more sources
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Alternation between different types of evidence attenuates judgments of severity. [PDF]
PLoS ONE, 2017 Most real-world judgments and decisions require the consideration of multiple types of evidence. For example, judging the severity of environmental damage, medical illness, or negative economic trends often involves tracking and integrating evidence from
Jennifer C Whitman +2 more
doaj +1 more source
Smart EMI monitoring of thin composite structures [PDF]
, 2011 This paper presents a structural health monitoring (SHM) method for in-situ damage detection and localization in carbon fibre reinforced plates (CFRP).
Cherrier, Olivier +4 more
core +1 more source
, 2004 For the new hadron collider LHC and some of its updates in luminosity and energy, as SLHC and VLHC, the silicon detectors could represent an important option, especially for the tracking system and calorimetry.
ALICE Collab +16 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source