Results 201 to 210 of about 875,259 (309)

Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells. [PDF]

open access: yesNAR Cancer, 2021
Reed MR   +7 more
europepmc   +1 more source

Toughening β‐Ga2O3 via Mechanically Seeded Dislocations

open access: yesAdvanced Functional Materials, EarlyView.
β‐Ga2O3 is promising for next‐generation semiconductors but its brittleness limits flexible and high‐precision applications. Here, mechanically seeded dislocations introduced by surface deformation improved damage tolerance in (001) β‐Ga2O3. Nanoindentation and characterization show dislocations suppress cleavage cracks by enabling stable plastic ...
Zanlin Cheng   +5 more
wiley   +1 more source

HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance. [PDF]

open access: yesOncol Rep, 2021
Zong B   +9 more
europepmc   +1 more source

Infrared Nanocrystals for Space Application: Hardness to Irradiations

open access: yesAdvanced Functional Materials, EarlyView.
This article investigates infrared HgTe nanocrystals under X‐ray and ion irradiation, revealing remarkable radiation hardness. It uncovers distinct degradation mechanisms and shows that the nanomaterial outperforms integrated electronics. The results position colloidal nanocrystals as promising candidates for resilient space and harsh‐environment ...
Alexandre Neyret   +22 more
wiley   +1 more source

Molecular dependencies and genomic consequences of a global DNA damage tolerance defect. [PDF]

open access: yesGenome Biol
de Groot D   +13 more
europepmc   +1 more source

Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation

open access: yesAdvanced Functional Materials, EarlyView.
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu   +9 more
wiley   +1 more source

Chloroxine overrides DNA damage tolerance to restore platinum sensitivity in high-grade serous ovarian cancer. [PDF]

open access: yesCell Death Dis, 2021
Silva VL   +6 more
europepmc   +1 more source

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