Results 161 to 170 of about 670,121 (313)

The effect of the number of response cycles on the behaviour of reinforced concrete elements subject to cyclic loading

open access: yes, 2012
The development of damage in reinforced concrete (RC) structures is a cumulative process. Some damage indices used to quantify damage make use of the number of response cycles as an Engineering Demand Parameter (EDP) relating with damage development ...
Varum, H., Rossetto, T., Borg, R. C.
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Elastic Damage Healing Model Coupling Secondary Damage Variable for Self Healing Materials

open access: yes
A one-dimensional constitutive model, based on the principles of continuum damage mechanics, is developed for capturing healing in certain materials during unloading and rest periods.
Subramanian, Harini, Mulay, Shantanu S
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Scalar damage variable determined in the uniaxial and triaxial compression conditions of sandstone samples

open access: yes, 2013
The article is based on the results of uniaxial and triaxial compression tests, performed on Wustenzeller sandstone. An overview of the possible definitions of damage variable describing the process of damage development on the basis of various ...
Cieślik, J.
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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