Results 141 to 150 of about 670,121 (313)
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Some Integral Formulas for Fatigue Damage in Variable Amplitude Loading
In this paper some integral formulas for the fatigue damage in variable amplitude loading are presented. The formulas, which in their original form appeared in Rychlik (1993), may be used for both the theoretical analysis of the fatigue damage, resulting
Lidström, Per,, Lund University.
core +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
This paper describes an experimental validation of the fatigue damaging events that were identified and extracted using a wavelet-based fatigue data editing technique.
Abdullah, S +7 more
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Homeowner satisfaction and service quality in the repair of UK flood-damaged domestic property [PDF]
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the Award of Degree of Doctor of PhilosophyFlooding is a global challenge that has plagued mankind throughout history, affecting over 164 million people ...
Samwinga, Victor
core
Resarch on Unloading Modulus for Salt Rock Damage Testing
:The uniaxial seven stress levels cyclic loading and unloading test for salt rock and marble were carried out on MTS815 Flex Test GT rock mechanics test system, and the damage unloading modulus were discussed. The loading test wave for low cyclic loading
刘建锋, 徐进, 裴建良, 张茹
doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source

