Results 61 to 70 of about 271,153 (306)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Multi-Scale Earthquake Damaged Building Feature Set
DataEarthquake disasters are marked by their unpredictability and potential for extreme destructiveness. Accurate information on building damage, captured in post-earthquake remote sensing images, is critical for an effective post-disaster emergency response.
Guorui Gao +8 more
doaj +1 more source
EVOLUTIONAL BUILDING DAMAGE PREDICTION
Journal of Structural and Construction Engineering (Transactions of AIJ), 2009 We hypothesized that the scale of the predicted Nankai Earthquake will increase gradually year by year as the time passes from the last occurrence in December 1946, and then we estimated strong motions chronologically from 2009 to 2060 for western Japan based on the up-to-date strong motion prediction method, i.e., the so-called statistical Green's ...
openaire +2 more sources
A pre-posterior analysis framework for quantifying the value of seismic monitoring and inspections of buildings [PDF]
, 2016 Peer ...
Limongelli, Maria Pina +2 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Impact of New Madrid Seismic Zone Earthquakes on the Central USA, Vol. 1 and 2 [PDF]
, 2009 The information presented in this report has been developed to support the Catastrophic Earthquake Planning Scenario workshops held by the Federal Emergency Management Agency.
Cleveland, Lisa J. +3 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Fragility of Hydraulic Elevators for Use in Performance-Based Earthquake Engineering [PDF]
, 2007 New performance-based earthquake engineering methods developed by the Pacific Earthquake Engineering Research Center, the Applied Technology Council, and others include damage analysis at a highly detailed level, requiring the compilation of fragility ...
Porter, Keith
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source