Results 131 to 140 of about 1,303,184 (394)

Implications of a lowered damage trajectory for mitigation in a continuous-time stochastic model [PDF]

open access: yes
This paper provides counterexamples to the idea that mitigation of greenhouse gases causing climate change, and adaptation to climate change, are always and everywhere substitutes.
Strand, Jon
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Long-term plasma exposure of ITER-like W/Cu monoblocks with pre-damaged surfaces in EAST experiments

open access: yesNuclear Fusion
In the ITER and future fusion devices, W/Cu monoblocks will be used as divertor target which are exposed to both steady state heat load and transient heat flux.
Zongxiao Guo   +12 more
doaj   +1 more source

Structural Response of a Two-Side-Supported Square Slab Under Varying Blast Positions from Center to Free Edge and Beyond in a Touch-Off Explosion Scenario

open access: yesBuildings
A touch-off explosion on concrete slabs is considered one of the simplest yet most destructive forms of adversarial loading on building elements. It causes far greater damage than explosions occurring at a distance.
S. M. Anas   +3 more
doaj   +1 more source

Media Exposure, Juror Decision-Making, and the Availability Heuristic [PDF]

open access: yes, 2012
Although much of the research regarding media exposure has centered on the harmful effects of pretrial publicity in criminal cases, it has been argued that civil cases may be more vulnerable to its effects compared to criminal cases (Bornstein ...
Crawford, Jessica, Platania, Judith
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Damages for Wrongful Death in Alaska [PDF]

open access: yes, 1988
I den här rapporten presenteras den forskning om ledarskap inom offentliga sektorn som bedrivs vid Linköpings universitet. Kartläggningen är indelad i fem olika teman: Chefers arbete och förutsättningar Ledarskap och lärande Genus och jämställdhet ...
Ingraham, Millard F.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Modelling bark beetle disturbances in a large scale forest scenario model to assess climate change impacts and evaluate adaptive management strategies [PDF]

open access: yes
To study potential consequences of climate-induced changes in the biotic disturbance regime at regional to national scale we integrated a model of Ips typographus (L. Scol. Col.) damages into the large-scale forest scenario model EFISCEN.
Lexer, M.J.   +3 more
core   +3 more sources

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