Results 211 to 220 of about 536,968 (249)

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian   +14 more
wiley   +1 more source

A superelastic titanium alloy showing nearly temperature-independent high strength and elastic modulus. [PDF]

open access: yesNat Commun
Chen B   +14 more
europepmc   +1 more source

Generative AI‐Enabled Discovery and Experimental Demonstration of Ultra‐Broadband Epsilon‐Near‐Zero Perfect Absorbers

open access: yesAdvanced Science, EarlyView.
Researchers developed and applied a generative artificial intelligence (AI) model to optimize epsilon‐near‐zero thin film stacks for ultra‐broadband perfect absorption of light. The fabricated AI‐designed absorber, with a total thickness of only 160 nm, experimentally demonstrated an absorption bandwidth exceeding 1000 nm while maintaining greater than
David Dang   +10 more
wiley   +1 more source

Q‐LEAP: Millisecond Hyperdimensional Optimization for Full‐Spectrum Optical Metamaterials

open access: yesAdvanced Science, EarlyView.
Q‐LEAP integrates physics‐informed residual machine learning with factorization‐machine‐encoded quantum annealing to design full‐spectrum optical metamaterials. It explores a 2108 design space and, in a single 2.56 ms annealing step, reaches 85.83% of the theoretical FoM limit, enabling selective 5‐8 µm emission with 3–5 and 8–14 µm suppression and ∼40×
Zikang Guo   +3 more
wiley   +1 more source

Immunomagnetic‐MXene Bifunctional Probes for Ultrasensitive and Specific Terahertz Metasensing of Tumor‐Derived Exosomes

open access: yesAdvanced Science, EarlyView.
An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin   +8 more
wiley   +1 more source

Optimization of milling operation parameters using Python-assisted GRA for enhanced surface quality and material behaviour. [PDF]

open access: yesRSC Adv
Selvaraj G   +11 more
europepmc   +1 more source

SPICE‐Compatible Compact Modeling of Cuprate‐Based Memristors Across a Wide Temperature Range

open access: yesAdvanced Electronic Materials, EarlyView.
A physics‐guided compact model for YBCO memristors is introduced, incorporating carrier trapping, field‐induced detrapping, and a differential balance equation to describe their switching dynamics. The model is compared with experiments and implemented in LTspice, allowing realistic circuit‐level simulations.
Thomas Günkel   +6 more
wiley   +1 more source

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