Advanced Science, EarlyView.Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi +17 more
wiley +1 more source
Numerical Simulation of the Post-Tensioned Beams Behaviour Under Impulse Forces Loading. [PDF]
Materials (Basel)Jancy A, Stolarski A.
europepmc +1 more source
Advanced Science, EarlyView.Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
Mechanical and Vibration Performance of Novel Lightweight Sandwich Structures with EPS Beads Filled Syntactic Foam Cores. [PDF]
ACS OmegaŞansveren MF, Yaman M.
europepmc +1 more source
The Importance of Metal‐Organic Framework Linker Atoms for CO2 Reduction: A DFT Study
Advanced Science, EarlyView.Using DFT, we examine the role of linker atoms in CO2 reduction on copper‐based metal organic frameworks (Cu MOFs). Our calculations reveal that linker atoms may serve as both CO2 and H‐shuttling sites and suggest linker electrostatics as a descriptor for linker activity. ABSTRACT Although the metal within the secondary building unit of a metal‐organic
Ugochukwu Nwosu, Samira Siahrostami
wiley +1 more source
Pendulum column with inclined negative stiffness as a novel hybrid seismic isolation mechanism integrated into soil with pile-like characteristics. [PDF]
Sci RepAzizi A, Barghian M.
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Advanced Science, EarlyView.Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma +17 more
wiley +1 more source
Numerical simulation of mechanical properties of a new type of assembly shear wall horizontal connection device. [PDF]
Sci RepTian P +5 more
europepmc +1 more source
Breaking the Toughness‐Stretchability Trade‐Off in Hydrogels with Dynamic Hydrogen Bonding
Advanced Science, EarlyView.A novel nanocomposite hydrogel architecture overcomes the inherent conflict between toughness and stretchability by integrating uniformly dispersed aminopropyl‐hybrid‐phyllosilicate nanosheets within a polyacrylamide matrix. This design leverages a dynamic hydrogen‐bonding network to facilitate efficient energy dissipation and self‐recovery.
Yining Gao +3 more
wiley +1 more source
Study on elastic-plastic displacement response spectra of base-isolated structures and its influencing factors. [PDF]
PLoS OneXu T, Wang Y, Qian S, Meng Q, Guo S.
europepmc +1 more source