Results 171 to 180 of about 123,674 (312)

Maternal Dyslipidaemia Aggravates Offspring Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

open access: yesBasic Clin Pharmacol Toxicol
Pedersen K   +4 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Spillway hydraulic issues in rebuilding embankment dams – experiences from Vattenfall’s dam-safety program

open access: yes, 2009
In the light of the revised design floods and higher dam-safety requirements, many dams, owned by Vattenfall, have been rebuilt and many others undergo dam-safety evaluations or an upgrading process. Depending upon the dam in question, hydraulic concerns
Yang, James,, Cederström, Malte
core  

Maternal Med12 safeguards trophoblast pluripotency and placental development. [PDF]

open access: yesBiol Reprod
Halstead MM   +5 more
europepmc   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

open access: yesEpilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson   +2 more
wiley   +1 more source

The 2025 Kamchatka Earthquake and Tsunami: Cascading Impacts and Risks to Japan

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT On July 29th, 2025, a large earthquake (Mw 8.8) occurred near the Kamchatka Peninsula. This event caused a tsunami that reached Japan's Pacific coast, even though the source was far away. In this study, we analyze the characteristics of earthquakes and tsunamis and discuss how they relate to the recurrence possibility and risk in Japan.
Ampan Laosunthara   +6 more
wiley   +1 more source

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