Results 191 to 200 of about 10,484 (237)

Danazol

2007
Danazol is an orally active synthetic, steroidal attenuated androgen and has the general properties of ...
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Danazol and Oral Anticoagulants

Scottish Medical Journal, 1982
A case report of overt bleeding in a young woman on warfarin given the anabolic steroid danazol for menorrhagia is reported. This interaction appears to be poorly recognised and we suggest that when commencing such a treatment the dose of anticoagulant should initially be halved and thereafter tailored to the thrombotest.
G. D. O. Lowe, M. Small, J. A. Thomson, G. McCune, M. Peterkin   +4 more
openaire   +3 more sources

Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study

The Lancet, 2023
S. Verstovsek, A. Gerds, A. Vannucchi, H. Al-Ali, D. Lavie, A. Kuykendall, S. Grosicki, A. Iurlo, Y. Goh, M. Lazaroiu, M. Egyed, M. Fox, D. Mclornan, A. Perkins, S. Yoon, V MNSSVKR GUPTA, J. Kiladjian, Nikki Granacher, Sung‐Eun Lee, L. Ocroteala, F. Passamonti, C. Harrison, B. Klencke, S. Ro, R. Donahue, J. Kawashima, R. Mesa, A. Abulafia, B. Andreasson, A. Angona, R. Ayala, S. Bang, B. Bank, F. Barraco, E. Beggiato, F. Benghiat, M. Bonifacio, C. Bories, G. Borsaru, M. Brabrand, A. Braester, Andes Broliden, V. Buxhofer-Ausch, N. Cambier, M. Caramella, B. Carpentier, N. Cascavilla, M. Castellano, Hung Chang, Chih-Cheng Chen, J. Cheong, Yunsuk Choi, P. Choi, M. Corsetti, I. Cuadrado, J. Cunningham, G. Damaj, V. Stefano, R. Delage, Regina Garcĺa Delgado, J. M. T. Diaz, P. Dombi, V. Dubruille, M. Egyed, D. Fassi, A. Elinder-Camburn, E. Elli, M. Ellis, C. Fava, Salman Fazal, Angela G. Fleischman, L. Foltz, L. Fox, N. Gabrail, Jose Valentĺn Garcĺa-Gutiérrez, A. Gerds, S. Girault, H. Gisslinger, Alexandru Gluvacov, J. Göthert, E. Hadjiev, K. Hafraoui, A. Hamed, C. Harrison, H. Hasselbalch, H. Hauser, M. Heaney, H. Hebart, J. H. Rivas, V. H. Saavedra, C. Hillis, H. Hou, J. How, Dan-chi Huang, M. Hus, Á. Illés, A. Isidori, Vadim G. Ivanov, Peter Johansson, C. Jung, I. Kirgner, M. Koren-Michowitz, S. Koschmieder, Szabolcs Kosztolányi, Natalia Kreiniz, A. Kuykendall, J. Lambert, K. Laribi, A. Lascaux, N. Lavie, M. Lazaroiu, Michael Leahy, E. Lech-Maranda, W. Lee, O. Legrand, R. Lemoli, James Liang, Sung-Nam Lim, Michael Loschi, A. Lucchesi, I. Macarie, J. Marolleau, M. Martelli, J. Mayer, J. Mccloskey, C. McDermott, Brandon McMahon, Priyanka Mehta, G. Mikala, D. Milojkovic, P. Mineur, E. Mishchenko, J. Moon, Z. Nagy, S. Narayanan, C. O'Connell, S. Oh, M. Ojeda-Uribe, K. Ong, F. Otegbeye, J. Palmer, F. Pane, A. Patriarca, G. Pietrantuono, M. Plander, U. Platzbecker, Ritam Prasad, W. Prejzner, T. Rachow, A. Radinoff, L. Rejtő, C. Rinaldi, T. Robak, M. Rodríguez, Aaron Ronson, D. Ross, T. Sacha, P. Sadjadian, A. Salar, G. S. Santillana, C. Scheid, Aline Schmidt, M. Severinsen, V. Stoeva, P. Szwedyk, M. Tiribelli, K. Trautmann-Grill, A. Trottier, N. Tzvetkov, J. Droogenbroeck, A. Vannucchi, N. Vianelli, N. Bubnoff, Dominik J. Wolf, D. Woszczyk, T. Woźny, T. Wróbel, B. Xicoy, S. Yeh   +178 more
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Impact of polymers on the precipitation behavior of highly supersaturated aqueous danazol solutions.

Molecular Pharmaceutics, 2014
The phase behavior of supersaturated solutions of a relatively hydrophobic drug, danazol, was studied in the absence and presence of polymeric additives.
M. Jackson, S. Toth, Umesh S. Kestur, Jun Huang, F. Qian, M. Hussain, G. Simpson, L. Taylor   +7 more
semanticscholar   +1 more source

Levels of androgens and danazol metabolites in serum during danazol therapy

Fertility and Sterility, 1993
Thirteen women who had endometriosis were treated with danazol (300 to 400 mg/d). Levels of androgens and danazol metabolites in serum and the influences of danazol metabolites on the assays for serum androgen were investigated during danazol therapy. Serum DHEAS significantly increased (P < 0.05), but serum DHEA slightly decreased.
Gen Yamashiro, Toshinobu Nakagawa, Kazutomo Akasofu, Kouichi Murakami, Katsumi Araki   +4 more
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An in vitro digestion test that reflects rat intestinal conditions to probe the importance of formulation digestion vs first pass metabolism in Danazol bioavailability from lipid based formulations.

Molecular Pharmaceutics, 2014
The impact of gastrointestinal (GI) processing and first pass metabolism on danazol oral bioavailability (BA) was evaluated after administration of self-emulsifying drug delivery systems (SEDDS) in the rat.
M. U. Anby, Tri-Hung Nguyen, Yan Yan Yeap, O. Feeney, H. Williams, H. Benameur, C. Pouton, C. Porter   +7 more
semanticscholar   +1 more source

Danazol and Erythema Multiforme

Annals of Internal Medicine, 1988
Excerpt To the Editor:Danazol was initially used for inhibition of the pituitary-ovarian axis and treatment of angioedema due to deficiency of C'1 esterase inhibitor.
Leonard E. Gately, W. Abe Andes
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Final Analysis of a Multicenter Pilot Phase 2 Study of Ruxolitinib and Danazol in Patients with Myelofibrosis

, 2015
Introduction: Most myelofibrosis (MF) patients develop anemia during evolution of the disease process predicting decreased survival. Previous studies exploring the effect of danazol for the treatment of anemia in MF demonstrate responses in anemia.
K. Gowin, H. Kosiorek, A. Dueck, J. Mascarenhas, R. Hoffman, C. Reeder, J. Camoriano, V. Fauble, R. Tibes, K. Gano, Vineta Ghurye, Patricia A. Koenig, R. Mesa   +12 more
semanticscholar   +1 more source

Danazol treatment of myelodysplastic syndromes

British Journal of Haematology, 2008
Peripheral cytopenias are common in patients with myelodysplastic syndromes. We previously successfully treated three such patients with improvement of some cytopenias with the impeded androgen danazol. To confirm this finding and elucidate the mechanism of response, we treated an additional 22 patients with myelodysplasia with oral danazol (600-800 mg
Janet L. Abrahm, Peter C. Nowell, Douglas B. Cines, Peter A. Cassileth, Alan D. Schreiber, Edward A. Stadtmauer, Marian Edelstein   +6 more
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Evaluation of selected angiogenic and inflammatory markers in endometriosis before and after danazol treatment.

Reproduction, Fertility and Development, 2014
Angiogenesis and inflammation are pivotal processes in developing endometriosis in the peritoneal cavity. The aim of the present study was to evaluate these two processes in women with endometriosis who had been treated with danazol to determine the ...
M. Szubert, J. Suzin, M. Duechler, Agata Szuławska, M. Czyż, K. Kowalczyk-Amico   +5 more
semanticscholar   +1 more source