Results 1 to 10 of about 111,576 (246)

Bradykinin-Mediated Angioedema Induced by Commonly Used Cardiovascular Drugs

Drugs and Drug Candidates, 2023
ACE inhibitors, sartans, and sacubitril are among the most important drugs for the prevention of cardiovascular mortality and morbidity. At the same time, they are known to cause non-allergic bradykinin-mediated angioedema, a potentially fatal swelling ...
Janina Hahn, Jens Greve, Murat Bas, Georg Kojda   +3 more
doaj   +1 more source

Brazilian Guidelines for Hereditary Angioedema Management - 2017 Update Part 1: Definition, Classification and Diagnosis

Clinics, 2018
Hereditary angioedema is an autosomal dominant disease characterized by recurrent angioedema attacks with the involvement of multiple organs. The disease is unknown to many health professionals and is therefore underdiagnosed.
Pedro Giavina-Bianchi, Luisa Karla Arruda, Marcelo V. Aun, Regis A. Campos, Herberto J. Chong-Neto, Rosemeire N. Constantino-Silva, Fátima R. Fernandes, Maria F. Ferraro, Mariana P.L. Ferriani, Alfeu T. França, Gustavo Fusaro, Juliana F.B. Garcia, Shirley Komninakis, Luana S.M. Maia, Eli Mansour, Adriana S. Moreno, Antonio A. Motta, João B. Pesquero, Nathalia Portilho, Nelson A. Rosário, Faradiba S. Serpa, Dirceu Solé, Priscila Takejima, Eliana Toledo, Solange O.R. Valle, Camila L. Veronez, Anete S. Grumach   +26 more
doaj   +1 more source

Hereditary angioedema with normal C1-inhibitor levels: a rare case report

Revista Portuguesa de Medicina Geral e Familiar
Hereditary angioedema (HAE) is a rare, hereditary disease and its manifestations may be life-threatening. It differs from histaminergic angioedema since it shows different underlying mechanisms and, therefore, does not respond to antihistamine or ...
Filipa Rodrigues dos Santos, Inês Falcão, Leonor Cunha   +2 more
doaj   +1 more source

Effective Management of Type III Hereditary Angioedema with Lanadelumab: A Case Report

Journal of Human Immunity
IntroductionHereditary angioedema is a rare disorder characterized by recurrent episodes of edema in the skin and mucous membranes caused by a quantitative or qualitative defect in the C1 inhibitor, with a consequent exaggerated production of bradykinin.
C.M. Chackelevicius, J.C. Abuin
doaj   +1 more source

Hospitalizations due to Angioedema without Urticaria in a Portuguese Center: Five Year Retrospective Study

Acta Médica Portuguesa, 2019
Introduction: Hospitalizations due to angioedema are important especially in debilitating or life-threatening situations. The aim of this study was to evaluate the frequency and etiology of angioedema without urticaria in hospital admissions.
Joana Cosme, Amélia Spínola, Manuel Branco Ferreira, Manuel Pereira Barbosa   +3 more
doaj   +1 more source

Recurrent Angioedema with Abdominal and Genital Involvement in Childhood: Hereditary Angioedema Type 2 Disease due to C1 Inhibitor Functional Deficiency

İstanbul Medical Journal, 2020
Hereditary angioedema is a rare disorder characterized by recurrent angioedema attacks due to C1 inhibitor antigen or functional deficiency. Here, two cases with recurrent swelling on extremities, genital organs and face that were later diagnosed with C1
Öner Özdemir, Halime Çiçek
doaj   +1 more source

Pathophysiology of Hereditary Angioedema [PDF]

American Journal of Rhinology & Allergy, 2011
Background Laryngeal angioedema may be associated with significant morbidity and even mortality. Because of the potential severity of attacks, both allergists and otolaryngologists must be knowledgeable about the recognition and treatment of laryngeal angioedema. This study describes the clinical characteristics
Bruce L, Zuraw, Sandra C, Christiansen
openaire   +2 more sources

Pediatric hereditary angioedema [PDF]

Pediatric Allergy and Immunology, 2013
Abstract Hereditary angioedema ( HAE ) is a lifelong illness characterized by recurrent swelling of the skin, intestinal tract, and, ominously, the upper airway. It is caused by inadequate activity of the protein C1‐inhibitor, with dysfunction in the kallikrein/bradykinin ...
openaire   +4 more sources

Novel SERPING1 Genetic Variant in Two Family Members with Hereditary Angioedema

Acta Médica Portuguesa
Hereditary angioedema is a rare, autosomal dominant, genetic disorder characterized by recurrent episodes of angioedema. Over 800 SERPING1 gene variants have been reported, and their clinical profiles and causal genetic variants are highly heterogeneous.
Sofia Cosme Ferreira, Alexandra Rosa, Filipa Sousa, Alejandro Mendoza-Alvarez, Rafaela González-Montelongo, Ariel Callero, Carlos Flores, Rita Câmara   +7 more
doaj   +1 more source

Membranous nephropathy in a patient with hereditary angioedema: a case report

Journal of Medical Case Reports, 2008
Introduction Hereditary angioedema is the commonest inherited disorder of the complement system and has been associated with several immune glomerular diseases.
Majoni Sandawana W, Smith Steven R
doaj   +1 more source