Results 31 to 40 of about 1,165 (100)

Salmonella Typhi asparaginase-dependent activation of GCN2 promotes bacterial killing in murine macrophages

open access: yesInfection and Immunity
Many intracellular pathogens stimulate host cell stress by directly or indirectly causing an imbalance in host nutrients. Depletion of amino acid pools, in particular, can act as a danger signal to infected cells.
Zachary M. Powers   +10 more
doaj   +1 more source

Activating PKC-ε induces HIV expression with improved tolerability.

open access: yesPLoS Pathogens
Despite suppressive antiretroviral therapy (ART), HIV-1 persists in latent reservoirs that seed new HIV infections if ART is interrupted, necessitating lifelong therapy for people with HIV.
Alivelu M Irrinki   +22 more
doaj   +1 more source

Restricted access to the NHS during the COVID-19 pandemic: Is it time to move away from the rationed clinical response?

open access: yesThe Lancet Regional Health. Europe, 2021
Daniel K Goyal, PhD   +9 more
doaj   +1 more source

Low-density lipoprotein cholesterol management and goal attainment at 1 year in patients with diabetes, pre-diabetes and normoglycaemia: results from the European, prospective, observational SANTORINI study

open access: yesBMJ Open
Objective To assess changes in lipid-lowering therapy (LLT) use and low-density lipoprotein cholesterol (LDL-C) goal attainment through 1-year follow-up in patients stratified by diabetes status in SANTORINI (Treatment of High and Very High riSk ...
  +585 more
doaj   +1 more source

Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trialResearch in context

open access: yesEClinicalMedicine
Summary: Background: Low dose corticosteroids (e.g., 6 mg dexamethasone) have been shown to reduce mortality for hypoxic COVID-19 patients. We have previously reported that higher dose corticosteroids cause harm in patients with clinical hypoxia but not
O. Abani   +8023 more
doaj   +1 more source

100 años de la American Economic Review: los 20 artículos más destacados [PDF]

open access: yesRevista de Economía Institucional, 2011
Kenneth J. Arrow   +5 more
doaj   +1 more source

Predictors of 30-Day Mortality in Trauma: A Single-Center Retrospective Exploratory Study. [PDF]

open access: yesLife (Basel)
Eremia IA   +7 more
europepmc   +1 more source

Ex Situ Management and Reproduction of the Rediscovered Yellow-Spotted Bell Frog, <i>Ranoidea castanea</i>. [PDF]

open access: yesAnimals (Basel)
McFadden MS   +6 more
europepmc   +1 more source

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