Results 21 to 30 of about 1,165 (100)

Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites

Nature Communications, 2021
Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified
Gaoqian Feng, Bruce D. Wines, Liriye Kurtovic, Jo-Anne Chan, Philippe Boeuf, Vanessa Mollard, Anton Cozijnsen, Damien R. Drew, Rob J. Center, Daniel L. Marshall, Sandra Chishimba, Geoffrey I. McFadden, Arlene E. Dent, Kiprotich Chelimo, Michelle J. Boyle, James W. Kazura, P. Mark Hogarth, James G. Beeson   +17 more
doaj   +1 more source

Trends in kidney function testing in UK primary care since the introduction of the quality and outcomes framework: a retrospective cohort study using CPRD

BMJ Open, 2019
Objectives To characterise serum creatinine and urinary protein testing in UK general practices from 2005 to 2013 and to examine how the frequency of testing varies across demographic factors, with the presence of chronic conditions and with the ...
Jason Oke, Rafael Perera, Christopher O’Callaghan, Jeffrey Aronson, Daniel Lasserson, Clare Taylor, Benjamin Feakins, Emily McFadden, Nathan Hill, Richard Stevens   +9 more
doaj   +1 more source

Propensity to obesity impacts the neuronal response to energy imbalance

Frontiers in Behavioral Neuroscience, 2015
The mechanisms responsible for the propensity to gain weight or remain normal weight are poorly understood. The objective of this study was to study the neuronal response to visual food cues during short-term energy imbalance in healthy adults recruited
Marc-Andre eCornier, Marc-Andre eCornier, Kristina Legget McFadden, Elizabeth A Thomas, Elizabeth A Thomas, Jamie L Bechtell, Jamie L Bechtell, Daniel H Bessesen, Daniel H Bessesen, Jason R Tregellas, Jason R Tregellas, Jason R Tregellas   +11 more
doaj   +1 more source

PRINCIPALES CONTRIBUCIONES DE LOS PREMIOS NOBEL DE ECONOMÍA DEL AÑO 2000

Economía y Sociedad, 2000
En el 2000 la Academia Real Sueca de Ciencias otorgó un premio Nobel compartido entre dos economistas cuyos aportes en los campos de la microeconometría, permitieron el descubrimiento de métodos ampliamente aplicados en el análisis estadístico de la ...
Rodrigo Briceño
doaj  

Applying eDNA Methods to Monitor the Distribution of Remnant and Translocated Populations of an Endangered Amphibian, Litoria booroolongensis

Environmental DNA
Effective conservation of threatened species relies on precise detection methods to inform conservation management strategies. Here, we developed a new environmental DNA (eDNA) assay to detect the endangered Booroolong frog (Litoria booroolongensis) in ...
Rebecca Wood, Daniel Coleman, Michael McFadden, Philip Spark, David Coote, Peta Hill, Elise Furlan   +6 more
doaj   +1 more source

CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

Cell Reports, 2018
Summary: Liver tissue-resident memory T (Trm) cells migrate throughout the sinusoids and are capable of protecting against malaria sporozoite challenge.
Lauren E. Holz, Julia E. Prier, David Freestone, Thiago M. Steiner, Kieran English, Darryl N. Johnson, Vanessa Mollard, Anton Cozijnsen, Gayle M. Davey, Dale I. Godfrey, Katsuyuki Yui, Laura K. Mackay, Mireille H. Lahoud, Irina Caminschi, Geoffrey I. McFadden, Patrick Bertolino, Daniel Fernandez-Ruiz, William R. Heath   +17 more
doaj   +1 more source

White paper on microbial anti-cancer therapy and prevention

Journal for ImmunoTherapy of Cancer, 2018
In this White Paper, we discuss the current state of microbial cancer therapy. This paper resulted from a meeting (‘Microbial Based Cancer Therapy’) at the US National Cancer Institute in the summer of 2017. Here, we define ‘Microbial Therapy’ to include
Neil S. Forbes, Robert S. Coffin, Liang Deng, Laura Evgin, Steve Fiering, Matthew Giacalone, Claudia Gravekamp, James L. Gulley, Hal Gunn, Robert M. Hoffman, Balveen Kaur, Ke Liu, Herbert Kim Lyerly, Ariel E. Marciscano, Eddie Moradian, Sheryl Ruppel, Daniel A. Saltzman, Peter J. Tattersall, Steve Thorne, Richard G. Vile, Halle Huihong Zhang, Shibin Zhou, Grant McFadden   +22 more
doaj   +1 more source

Exposure to low doses of Batrachochytrium dendrobatidis reveals variation in resistance in the Critically Endangered southern corroboree frog

Global Ecology and Conservation
Emerging infectious diseases, such as chytridiomycosis caused by Batrachochytrium dendrobatidis (Bd), pose a significant extinction threat to amphibians, including the Critically Endangered southern corroboree frog (Pseudophryne corroboree ...
Mikaeylah J. Davidson, Lee Berger, Amy Aquilina, Melissa Hernandez Poveda, Daniel Guinto, Michael McFadden, Deon Gilbert, Damian Goodall, Kyall R. Zenger, Lee F. Skerratt, Tiffany A. Kosch   +10 more
doaj   +1 more source

CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria.

PLoS Pathogens, 2014
To follow the fate of CD8+ T cells responsive to Plasmodium berghei ANKA (PbA) infection, we generated an MHC I-restricted TCR transgenic mouse line against this pathogen.
Lei Shong Lau, Daniel Fernandez-Ruiz, Vanessa Mollard, Angelika Sturm, Michelle A Neller, Anton Cozijnsen, Julia L Gregory, Gayle M Davey, Claerwen M Jones, Yi-Hsuan Lin, Ashraful Haque, Christian R Engwerda, Catherine Q Nie, Diana S Hansen, Kenneth M Murphy, Anthony T Papenfuss, John J Miles, Scott R Burrows, Tania de Koning-Ward, Geoffrey I McFadden, Francis R Carbone, Brendan S Crabb, William R Heath   +22 more
doaj   +1 more source

Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii.

PLoS Neglected Tropical Diseases
Relapsing fever (RF), a vector-borne disease caused by Borrelia spp., is characterized by recurring febrile episodes due to repeated bouts of bacteremia.
Clay D Jackson-Litteken, Wanfeng Guo, Brandon A Hogland, C Tyler Ratliff, LeAnn McFadden, Marissa S Fullerton, Daniel E Voth, Ryan O M Rego, Jon S Blevins   +8 more
doaj   +1 more source