Results 101 to 110 of about 46,128 (270)

Prioritising research on endocrine disruption in the marine environment: a global perspective

open access: yesBiological Reviews, EarlyView.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto   +23 more
wiley   +1 more source

Zebrafish models of developmental epileptic encephalopathy accurately reflect clinical electrographic biomarkers

open access: yesEpilepsia, EarlyView.
Abstract Objective Developmental epileptic encephalopathies (DEEs) are epilepsy conditions characterized by significant severity and treatment challenges. Spectral components of the encephalogram (EEG) may provide a valuable biomarker of epileptic severity.
Paige Whyte‐Fagundes   +3 more
wiley   +1 more source

In vivo targeted and deterministic single-cell malignant transformation

open access: yeseLife
Why does a normal cell possibly harboring genetic mutations in oncogene or tumor suppressor genes becomes malignant and develops a tumor is a subject of intense debate.
Pierluigi Scerbo   +5 more
doaj   +1 more source

Exposure to the Oestrogenic Pollutant 17α‐Ethinyl Estradiol (EE2) Does Not Alter the Behaviour of a Coastal Marine Fish, Cristiceps australis

open access: yesEthology, EarlyView.
Environmental contamination with the synthetic estrogen 17α‐ethinyl estradiol (EE2) is widespread in coastal ecosystems, yet behavioural effects in marine fishes remain poorly understood. We exposed southern crested weedfish (Cristiceps australis) to low and high EE2 concentrations for 14 days and assessed boldness and anxiety using a refuge‐use assay.
Shiho Ozeki   +6 more
wiley   +1 more source

A Review of Phage Therapy for Aquaculture Applications: Efficacy, Health Ramifications and Research Challenges

open access: yesFish and Fisheries, EarlyView.
Bacteriophage therapy is characterised by numerous advantages, facilitating its diverse aquaculture application and efficacy as an antibiotic alternative mitigating the spread of antimicrobial‐resistant pathogens. Contributing to the modern reappraisal of the aquaculture application of bacteriophage therapy, challenges impeding its widespread ...
Louise James   +4 more
wiley   +1 more source

A New Analytical Method for Calcium Quantification in Danio rerio Scales

open access: green, 2021
Marta Carnovali   +3 more
openalex   +2 more sources

Protein tandem repeats that produce frameshifts can generate new structural states and functions

open access: yesThe FEBS Journal, EarlyView.
We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli   +8 more
wiley   +1 more source

RESPOSTA MORFOLÓGICA DO CORAÇÃO DE ZEBRAFISH (Danio rerio) DECORRENTES DE DIETA HIPERCALÓRICA E EXERCÍCIO FÍSICO

open access: diamond, 2023
G. P. MENDES   +5 more
openalex   +2 more sources

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

open access: yesThe FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim   +8 more
wiley   +1 more source

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