Results 261 to 270 of about 115,181 (383)

Homoeolog expression in polyploid wheat mutants shows limited transcriptional compensation

open access: yes
New Phytologist, Volume 249, Issue 1, Page 16-23, January 2026.
Delfi Dorussen   +3 more
wiley   +1 more source

Identification of a Proteolysis‐Targeting‐Chimera that Addresses Activated Checkpoint Kinase‐1 Reveals its Non‐Catalytic Functions in Tumor Cells

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 49, December 1, 2025.
In cancer cells, the induction of DNA replication stress by HU activates CHK1 by autophosphorylation. This leads to cell cycle arrest and recruits the DNA repair protein WRN to promote DNA repair and cell survival. In such cells, addition of the CHK1 inhibitor 9a propels DNA damage and apoptosis.
Ramy Ashry   +13 more
wiley   +1 more source

Synthesis, Photophysical Properties, and Practical Hg(II)‐Sensing Applications of a Rigidified Phenolo‐Merocyanine Dye

open access: yesChemistry – An Asian Journal, Volume 20, Issue 23, December 2, 2025.
Rigidity for performance!!! A novel conformationally restrained phenolic merocyanine was synthesized in order to obtain a fluorogenic dye with outstanding spectral properties at physiological pH (fluorescence brightness > 71,000 M−1 cm−1). The utility of its optically tunable hydroxyl group was illustrated with a thiophosphinate‐based chemodosimeter ...
Kévin Renault   +6 more
wiley   +1 more source

Zebrafish: A Versatile and Powerful Model for Biomedical Research

open access: yesBioEssays, Volume 47, Issue 12, December 2025.
Zebrafish are vital for advancing precision medicine, offering a genetically tractable and optically transparent vertebrate model with strong genetic homology to humans. They enable rapid and cost‐effective disease modeling and drug discovery, accelerating insights into cardiovascular, neurological, metabolic, and oncological disorders through gene ...
Sundus Siddiqui   +3 more
wiley   +1 more source

Kanauninko Jurgio Danio veikia

open access: yes, 2010
Reikšminiai žodžiai: Bažnyčia; Biografija; Humanizmas; Jurgis Danys; Kanauninkas Jurgis Danys; Linkuva; Linkuvos parapija; Sielovada; Tolerancija; Veikla; Activity; Biography; Canon Jurgis Danys; Church; Humanism; Jurgis Danys; Linkuva; Linkuva parish; Lithuania; Pastoral activity ...
openaire   +1 more source

Alternative Splicing of SORBS1 Affects Neuromuscular Junction Integrity in Myotonic Dystrophy Type 1

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Myotonic dystrophy type 1 (DM1) is a multisystemic neuromuscular disorder characterized by CTG repeat expansion in the 3′ untranslated region of the dystrophia myotonica protein kinase coding gene. The presence of expanded CTG repeats in DMPK mRNAs leads to the sequestration of RNA‐binding factors such as the Muscleblind‐like (MBNL)
Caroline Hermitte   +11 more
wiley   +1 more source

Genomic and genetic insights into speciation and pigment pattern diversification in Danio fishes

open access: yes
Lu J   +19 more
europepmc   +1 more source

The hybrid history of zebrafish. [PDF]

open access: yesG3 (Bethesda)
McCluskey BM, Batzel P, Postlethwait JH.
europepmc   +1 more source

Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)

open access: gold
Franziska Auer   +4 more
openalex   +1 more source

Influence of mercury chloride on adenosine deaminase activity and gene expression in zebrafish (Danio rerio) brain

open access: gold, 2010
Mário Roberto Senger   +5 more
openalex   +2 more sources

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