Results 101 to 110 of about 38,235 (260)

Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov, Hans Bräuner, Alexander Sebastian Hauser   +2 more
wiley   +1 more source

Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model. [PDF]

Catheter Cardiovasc Interv
ABSTRACT Background Novel stent technologies offer early intravascular treatment options for coarctation (COA). Mid‐to‐long‐term cardiovascular responses to early COA stent interventions are undefined. Aims We studied a porcine model of COA, with and without early stent implantation with serial dilation to adult aortic diameters, aiming to define ...
Gober LM, Stellon MA, Culver MA, Frenkel A, Irrer D, Witzenburg CM, Roldán-Alzate A, Lamers L.   +7 more
europepmc   +2 more sources

Challenges and Coping Strategies of Migrant Parents in Türkiye: A Qualitative Study

Child &Family Social Work, EarlyView.
ABSTRACT This qualitative study explored the coping mechanisms used by 22 immigrant parents (nine men, 13 women) of Syrian, Iraqi, Afghan and Palestinian origin in Türkiye to cope with challenges related to food, shelter, healthcare and social exclusion while caring for their children.
Murat Altuntaş, Habibullah Akinci
wiley   +1 more source

Navigating the Activist Techno‐Social Landscape: Washington, DC High School Students' Engagement with Social Media Content

Children &Society, EarlyView.
ABSTRACT In recent decades, youth activism has experienced a global resurgence, playing a pivotal role in advocating for social and political change across diverse national and international contexts. Drawing on empirical data from a study of high school students in diverse Washington, DC public schools, this paper offers a unique perspective on youth ...
Vanessa R. Sperduti, Miri Yemini, Laura Engel, Garth Stahl   +3 more
wiley   +1 more source

Bioethics and the World Order: A Curious Coincidence Between Chinese and African Approaches

Developing World Bioethics, EarlyView.
ABSTRACT The post‐1945 world order is standardly pictured as a Westphalian system, in which each state is equal under the law with sovereign authority over its territories. This paper argues that the Westphalian system is changing and examines the implications for bioethics. We show that cross‐border health, economic, ecologic, and sociopolitical risks
Nancy S. Jecker, Jing‐Bao Nie, Anita Ho   +2 more
wiley   +1 more source

DECENTRALIZED AUTONOMOUS ORGANIZATION (DAO)

Iustinianus Primus Law Review, 2019
Simultaneously with the fall of the Berlin wall, we witnessed the process of general acceptance of the Internet as mainstream. Opportunities created in the last 30 years by the Internet, and particularly in the last 10 years with the dramatic increase ...
Andrej Ilievski
doaj  

Note on warped compactification. Finite brane potentials and non-Hermiticity

Journal of High Energy Physics
We study radius stabilization in the Randall-Sundrum model without assuming any unnaturally large stabilizing scalar potential parameter at the boundary branes (γ) by the frequently used superpotential method.
Sudhakantha Girmohanta, Yuichiro Nakai, Motoo Suzuki, Yaoduo Wang, Junxuan Xu   +4 more
doaj   +1 more source

Toward food-grade production of the Glutamicibacter halophytocola diamine oxidase using Komagataella phaffii

AMB Express
The diamine oxidase from Glutamicibacter halophytocola (DAO-GH) was recombinantly produced in K. phaffii using the constitutive glyceraldehyde-3-phosphate dehydrogenase promoter for methanol-free production. Firstly, K.
Anna Bechtel, Lucas Kettner, Jan Hessenberger, Kenny Vlassakakis, Lutz Fischer   +4 more
doaj   +1 more source

New organizational forms: Deconstructing and reconfiguring the literature

European Management Review, EarlyView.
Abstract Less hierarchical, self‐managing, agile, alternative: so‐called “new organizational forms” draw interest from scholars and practitioners alike. Despite an abundance of both conceptual and empirical research, the “new organizational form” concept remains elusive, capturing a growing diversity of phenomena and labels.
Constantin Bremer
wiley   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source