Results 141 to 150 of about 3,829 (256)

Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 23, Page 6865-6882, December 2026.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov   +2 more
wiley   +1 more source

Hip Hop as Linguistic and Sensory Contact Zones: Sounds and Rhythms of Vietnamese Rap and Dance in Munich and Hanoi

open access: yesCity &Society, Volume 38, Issue 3, December 2026.
ABSTRACT In this article, I draw on multi‐sited and remote ethnography in the cities of Munich in Germany and Hanoi in Vietnam to analyze how young hip hop artists transform cities as sensory contact zones through rap and dance. I show how young Vietnamese‐Germans amplify sensory contact zones in the diasporic city of Munich through the sounds, visuals,
Sandra Kurfürst
wiley   +1 more source

Exploring EFL Learners' Basic Psychological Needs, Grit and Willingness to Communicate in Blended Learning

open access: yesEuropean Journal of Education, Volume 61, Issue 4, December 2026.
ABSTRACT The increasing adoption of blended learning in English as a Foreign Language (EFL) education has intensified scholarly interest in the psychological factors associated with learners' communicative participation. Despite growing evidence linking motivational and affective variables to language learning outcomes, the combined relationships among
Chaofan Jiang, Yunhua Deng
wiley   +1 more source

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

open access: yesAnnals of Neurology, Volume 100, Issue 5, Page 948-961, November 2026.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl   +10 more
wiley   +1 more source

Genomic Alterations in Pulmonary Carcinoid Tumors: A Targeted Analysis of Gene Rearrangements and Oncogenic Mutations

open access: yesCancer Medicine, Volume 15, Issue 11, November 2026.
This study applied RNA‐based next‐generation sequencing to one of the largest cohorts of pulmonary carcinoid tumors analyzed to date and revealed rare yet potentially actionable gene rearrangements and variants, including alterations in ALK, BRAF, and EGFR.
Jenni Niinimäki   +4 more
wiley   +1 more source

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