Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang +9 more
wiley +1 more source
Sugarcane root system depth in three different countries [PDF]
THE SUGARCANE root system depth is crucial as it determines the potential depth of soil available for water and nutrient uptake by the crop. It was reported in an early publication that these roots could grow quite deep (6 m), but otherwise very little ...
Azevedo, M.C.B. +3 more
core
The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang +8 more
wiley +1 more source
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang +18 more
wiley +1 more source
SIKB0102: Synchronizing Excavation Data for Preservation and Re-Use
Key issue in re-using data from excavations is the need to understand the meaning of the contents. Integrating studies have a hard time using old datasets, for obvious reasons like finding the right data in the first place, understanding unknown codes ...
Wouter Boasson, Ronald M. Visser
doaj +1 more source
Functional characterization of a melon alcohol acyl-transferase gene family involved in the biosynthesis of ester volatiles. Identification of the crucial role of a threonine residue for enzyme activity [PDF]
Volatile esters, a major class of compounds contributing to the aroma of many fruit, are synthesized by alcohol acyl-transferases (AAT). We demonstrate here that, in Charentais melon (Cucumis melo var.
A. Aggelis +53 more
core +2 more sources
PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su +7 more
wiley +1 more source
Enfermedad renal crónica en Atención Primaria: prevalencia y factores de riesgo asociados
Objetivo: Conocer la prevalencia y los estadios de la enfermedad renal crónica según la estimación del filtrado glomerular (eFG), y los factores de riesgo asociados en individuos ≥ 60 años. Diseño: Estudio observacional transversal.
Betlem Salvador González +5 more
doaj +1 more source
Organic and conventional tomato cropping systems. [PDF]
Among several alternative agricultural systems have been developed, organic agriculture has deserved increasing interest from. The objective of this paper was comparing both organic (OS) and conventional (CS) tomato cropping systems for varieties Débora ...
ABBASI P.A. +16 more
core +3 more sources
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu +18 more
wiley +1 more source

