Results 71 to 80 of about 77,247 (255)

Operational research projects in DAP : an annotated inventory

, 1996
ONLINEWHO/DAP/96.389 ...
WHO Action Programme on Essential Drugs
core  

MurNAc‐Based Electrophilic Inhibitors of O‐Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, and Kinetic Evaluation

Chemistry – A European Journal, EarlyView.
A series of N‐acetylmuramic acid (MurNAc)‐based electrophilic inhibitors targeting Ape esterase was synthesized. Their inhibitory potency ranged from micromolar to submillimolar. The study probed binding contributions of stem peptide extension, replacing the anomeric methyl group with a benzyl, and α‐fluorination of the carbonyl to enhance ...
Dmytro Voskoboinyk, Martin E. Tanner
wiley   +1 more source

Transcriptome and proteome analyses reveal divergent adaptive strategies in nasopharyngeal epithelial cells and nasopharyngeal carcinoma cells under ultra‐low background radiation

Deep Underground Science and Engineering, EarlyView.
This study demonstrates that the ultra‐low background radiation environment in deep underground laboratories significantly inhibits the proliferation of both normal nasopharyngeal epithelial cells (HNEPC) and nasopharyngeal carcinoma cells (HNE‐1) cells, with malignant cells exhibiting higher sensitivity.
Yuhao Zou, Qi Wu, Jirui Wen, Ling Wang, Can Li, Juan Cheng, Tengfei Ma, Chuhan Lv, Shixi Liu, Mingzhong Gao, Ruihua Dong, Jianxiong Zhang, Jingxuan Wu, Heping Xie, Jiang Wu, Jifeng Liu   +15 more
wiley   +1 more source

Drosophila male genitalia rotation depends on permissive remodeling of the posterior abdomen

Developmental Dynamics, EarlyView.
Abstract Background One of the most characteristic morphogenetic processes in Drosophila is the 360° rotation of the male pupal genital disc. This movement is driven by the myosin Myo1D, whose expression in the genital disc is controlled by the Hox gene Abdominal‐B (Abd‐B).
Nuria Prieto, David Foronda, Paloma Martín, Eléanor Simon, Marcus Bischoff, Stéphane Noselli, Ernesto Sánchez‐Herrero   +6 more
wiley   +1 more source

Assessing the Vulnerability of Ramsar Wetlands Through an Ecological Character-Based Framework: A Case Study of Bau Sau, Vietnam

World
Wetland vulnerability assessment is essential for identifying interacting pressures, detecting potential changes in ecological character, and supporting adaptive management of Ramsar Sites.
Nguyen Dinh Dap
doaj   +1 more source

Fire‐Safe Polymeric Insulation Foams for Energy‐Efficient and Low‐Carbon Buildings

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review systematically summarizes recent advances in fire‐safe polymeric insulation foams, emphasizing the balance among flame retardancy, thermal insulation, mechanical reliability, and long‐term durability. By linking material‐level thermophysical properties with building cooling‐energy demand and operational carbon emissions, it establishes a ...
Qinhe Guo, Jiayi Pan, Dehui Jia, Min Chen, Danni Pan, Yao Yuan, Ying Pan, Yan Zhang, Lulu Xu, Kate Nguyen, Wei Wang   +10 more
wiley   +1 more source

Vaccination with a Live Avirulent E. coli Vaccine Resulted in Improved Production Performance Combined with a Significant Reduction in Antimicrobial Use

Antibiotics
Background/Objectives: In swine production, the post-weaning period has been identified as one of the most challenging and stressful periods in the life of a piglet due to changes in its environment and feeding regimen.
Frédéric Vangroenweghe, Thomas Matthijs, Marnix Sinnaeve   +2 more
doaj   +1 more source

Wearable performance [PDF]

, 2009
This is the post-print version of the article. The official published version can be accessed from the link below - Copyright @ 2009 Taylor & FrancisWearable computing devices worn on the body provide the potential for digital interaction in the world. A
Danjoux, Michele, Danjoux, M, Birringer, J, Birringer, Johannes, Michèle Danjoux, Johannes Birringer   +5 more
core   +1 more source

Bromonitroalkanes in Organic Synthesis

European Journal of Organic Chemistry, EarlyView.
α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical, carbanion, and carbocation synthons. This mini‐review summarizes the different reaction modes and highlights recent developments in thermal and photochemical processes. α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical,
Magdalena Koch, Oliver Reiser
wiley   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source